(A) Immunostaining of 14.5 dpc XY testis of wild type and TES-/- embryos on a Sox8-null background. (B) Immunostaining of 8 week-old XY testes of wild type and TES-/- mice on a Sox8-null background. Testes were stained for SOX9 (green), FOXL2 (red) and DAPI (blue). (C) Gene expression in XY TES deleted gonads with Sox8-null background at 14.5 dpc. Data are presented as mean 2-ΔΔCt values normalized to Hprt. Sample size represents number of individuals and is indicated below each genotype. Error bars show SEM of 2-ΔΔCt values. P value is presented above the relevant bars (unpaired, two-tailed t-test on 2-ΔΔCt values). Dark grey bars: XY; light grey bars: XX.
Citation: Gonen N, Quinn A, O’Neill HC, Koopman P, Lovell-Badge R (2017) Correction: Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone. PLoS Genet 13(2): e1006584. https://doi.org/10.1371/journal.pgen.1006584
Published: February 1, 2017
Copyright: © 2017 Gonen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.