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Correction: Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone

  • Nitzan Gonen,
  • Alexander Quinn,
  • Helen C. O’Neill,
  • Peter Koopman,
  • Robin Lovell-Badge

Correction: Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone

  • Nitzan Gonen, 
  • Alexander Quinn, 
  • Helen C. O’Neill, 
  • Peter Koopman, 
  • Robin Lovell-Badge
PLOS
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Errors were introduced during the production process resulting in the incorrect labelling of the genotypes in Fig 5C. Please view the correct Fig 5 here.

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Fig 5. Immunofluorescence and real-time quantitative RT-PCR analysis of mice carrying TES deletion on Sox8-null background.

(A) Immunostaining of 14.5 dpc XY testis of wild type and TES-/- embryos on a Sox8-null background. (B) Immunostaining of 8 week-old XY testes of wild type and TES-/- mice on a Sox8-null background. Testes were stained for SOX9 (green), FOXL2 (red) and DAPI (blue). (C) Gene expression in XY TES deleted gonads with Sox8-null background at 14.5 dpc. Data are presented as mean 2-ΔΔCt values normalized to Hprt. Sample size represents number of individuals and is indicated below each genotype. Error bars show SEM of 2-ΔΔCt values. P value is presented above the relevant bars (unpaired, two-tailed t-test on 2-ΔΔCt values). Dark grey bars: XY; light grey bars: XX.

https://doi.org/10.1371/journal.pgen.1006584.g001

Reference

  1. 1. Gonen N, Quinn A, O’Neill HC, Koopman P, Lovell-Badge R (2017) Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone. PLoS Genet 13(1): e1006520. pmid:28045957