Figures
Chromosome fusion occurring within a colony of Vibrio cholerae.
In their study, Val et al. show how reorganizing the genome of bacteria in a deliberate manner can help solve biological issues. In this image, blue sectors within a colony of the pathogen Vibrio cholerae indicate successful fusion of the two chromosomes to form a synthetic mono-chromosomal strain by directed site-specific recombination. This mono-chromosomal strain was further used to demonstrate that Dam, RctB, and ParA2/ParB2 factors are only essential for chrII maintenance.
Image Credit: Thibault Rouxel and Marie-Eve Val (Institut Pasteur)
Citation: (2012) PLoS Genetics Issue Image | Vol. 8(1) January 2012. PLoS Genet 8(1): ev08.i01. https://doi.org/10.1371/image.pgen.v08.i01
Published: January 26, 2012
Copyright: © 2012 Rouxel and Val . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
In their study, Val et al. show how reorganizing the genome of bacteria in a deliberate manner can help solve biological issues. In this image, blue sectors within a colony of the pathogen Vibrio cholerae indicate successful fusion of the two chromosomes to form a synthetic mono-chromosomal strain by directed site-specific recombination. This mono-chromosomal strain was further used to demonstrate that Dam, RctB, and ParA2/ParB2 factors are only essential for chrII maintenance.
Image Credit: Thibault Rouxel and Marie-Eve Val (Institut Pasteur)