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Open Access
Peer-reviewed
Research Article
Ash1l Methylates Lys36 of Histone H3 Independently of Transcriptional Elongation to Counteract Polycomb Silencing
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Hitomi Miyazaki ,
Contributed equally to this work with: Hitomi Miyazaki, Ken Higashimoto, Yukari Yada
Affiliations Division of Molecular Genetics and Epigenetics, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga City, Saga, Japan, Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Agency (JST), 4-1-8 Honcho, Kawaguchi City, Saitama, Japan
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Ken Higashimoto ,
Contributed equally to this work with: Hitomi Miyazaki, Ken Higashimoto, Yukari Yada
Affiliation Division of Molecular Genetics and Epigenetics, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga City, Saga, Japan
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Yukari Yada ,
Contributed equally to this work with: Hitomi Miyazaki, Ken Higashimoto, Yukari Yada
Affiliation Division of Gene Expression, Department of Developmental Genetics, National Institute of Genetics, 1111 Yata, Mishima City, Shizuoka, Japan
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Takaho A. Endo ,
¶TAE and JS also contributed equally to this work.
Affiliation RIKEN Center for Integrative Medical Sciences, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, Japan
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Jafar Sharif ,
¶TAE and JS also contributed equally to this work.
Affiliation RIKEN Center for Integrative Medical Sciences, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, Japan
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Toshiharu Komori,
Affiliations Division of Gene Expression, Department of Developmental Genetics, National Institute of Genetics, 1111 Yata, Mishima City, Shizuoka, Japan, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 Nagatsuta, Yokohama City, Kanagawa, Japan
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Masashi Matsuda,
Affiliation RIKEN Center for Integrative Medical Sciences, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, Japan
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Yoko Koseki,
Affiliation RIKEN Center for Integrative Medical Sciences, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, Japan
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Manabu Nakayama,
Affiliation Laboratory of Medical Genomics, Department of Human Genome Research, Kazusa DNA Research Institute, 2-6-7 Kazusa-kamatari, Kisarazu City, Chiba, Japan
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Hidenobu Soejima,
Affiliation Division of Molecular Genetics and Epigenetics, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga City, Saga, Japan
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Hiroshi Handa,
Affiliation Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 Nagatsuta, Yokohama City, Kanagawa, Japan
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Haruhiko Koseki,
Affiliations RIKEN Center for Integrative Medical Sciences, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, Japan, Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), 4-1-8 Honcho, Kawaguchi City, Saitama, Japan
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Susumu Hirose,
Affiliation Division of Gene Expression, Department of Developmental Genetics, National Institute of Genetics, 1111 Yata, Mishima City, Shizuoka, Japan
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Kenichi Nishioka
* E-mail: nshoka@cc.saga-u.ac.jp
Affiliations Division of Molecular Genetics and Epigenetics, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga City, Saga, Japan, Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Agency (JST), 4-1-8 Honcho, Kawaguchi City, Saitama, Japan, Division of Gene Expression, Department of Developmental Genetics, National Institute of Genetics, 1111 Yata, Mishima City, Shizuoka, Japan
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Ash1l Methylates Lys36 of Histone H3 Independently of Transcriptional Elongation to Counteract Polycomb Silencing
- Hitomi Miyazaki,
- Ken Higashimoto,
- Yukari Yada,
- Takaho A. Endo,
- Jafar Sharif,
- Toshiharu Komori,
- Masashi Matsuda,
- Yoko Koseki,
- Manabu Nakayama,
- Hidenobu Soejima
- Published: November 7, 2013
- https://doi.org/10.1371/journal.pgen.1003897