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Open Access
Peer-reviewed
Research Article
Balancing Selection on a Regulatory Region Exhibiting Ancient Variation That Predates Human–Neandertal Divergence
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Omer Gokcumen ,
Contributed equally to this work with: Omer Gokcumen, Qihui Zhu, Lubbertus C. F. Mulder
Affiliations Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
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Qihui Zhu ,
Contributed equally to this work with: Omer Gokcumen, Qihui Zhu, Lubbertus C. F. Mulder
Affiliations Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
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Lubbertus C. F. Mulder ,
Contributed equally to this work with: Omer Gokcumen, Qihui Zhu, Lubbertus C. F. Mulder
Affiliation Department of Microbiology, Mount Sinai School of Medicine, New York, New York, United States of America
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Rebecca C. Iskow,
Affiliations Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
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Christian Austermann,
Affiliation Department of Microbiology, Mount Sinai School of Medicine, New York, New York, United States of America
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Christopher D. Scharer,
Affiliation Department of Microbiology, Emory University, Atlanta, Georgia, United States of America
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Towfique Raj,
Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America
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Jeremy M. Boss,
Affiliation Department of Microbiology, Emory University, Atlanta, Georgia, United States of America
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Shamil Sunyaev,
Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America
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Alkes Price,
Affiliations Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America
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Barbara Stranger,
Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America
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Viviana Simon ,
* E-mail: viviana.simon@mssm.edu (VS); clee@rics.bwh.harvard.edu (CL)
¶These authors were joint senior authors on this work.
Affiliations Department of Microbiology, Mount Sinai School of Medicine, New York, New York, United States of America, Global Health and Emerging Pathogens Institute, New York, New York, United States of America, Division of Infectious Diseases, Department of Medicine, New York, New York, United States of America
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Charles Lee
* E-mail: viviana.simon@mssm.edu (VS); clee@rics.bwh.harvard.edu (CL)
¶These authors were joint senior authors on this work.
Affiliations Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
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Balancing Selection on a Regulatory Region Exhibiting Ancient Variation That Predates Human–Neandertal Divergence
- Omer Gokcumen,
- Qihui Zhu,
- Lubbertus C. F. Mulder,
- Rebecca C. Iskow,
- Christian Austermann,
- Christopher D. Scharer,
- Towfique Raj,
- Jeremy M. Boss,
- Shamil Sunyaev,
- Alkes Price
- Published: April 11, 2013
- https://doi.org/10.1371/journal.pgen.1003404