Cowc_CAOG_00155T0 CDC45 cell division cycle 45 homolog (S. cerevisiae) Cowc_CAOG_00358T0 FYRC Cowc_CAOG_00535T0 AURKA Aurora kinase Cowc_CAOG_00634T0 NDC80 NDC80 kinetochore complex component, homolog (S. cerevisiae) Cowc_CAOG_00725T0 Thymidylate synthase Cowc_CAOG_00768T0 H2A Histone H2A Cowc_CAOG_00769T0 HIRA B motif Cowc_CAOG_00815T0 MSH6 DNA mismatch repair protein MSH6 Cowc_CAOG_00902T0 KIF15 kinesin family member 15 Cowc_CAOG_01088T0 TBC Cowc_CAOG_06081T0 FG00667.1 WD domain, G-beta repeat Cowc_CAOG_06729T0 CENPE centromere protein E, 312kDa Cowc_CAOG_06766T0 transporter Cowc_CAOG_06923T0 KIF11 kinesin family member 11 Cowc_CAOG_07029T0 POLE polymerase (DNA directed), epsilon, catalytic subunit Cowc_CAOG_07034T0 FEN1 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double- stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA Cowc_CAOG_07056T0 Pfam:HIM Cowc_CAOG_07107T0 Pfam:HIM Cowc_CAOG_07549T0 KAR3 Kinesin family protein (KlpA) Cowc_CAOG_07647T0 CCNB2 g2 mitotic-specific Cowc_CAOG_07450T0 AHNAK nucleoprotein Cowc_CAOG_07453T0 PGUG_03004 CRAL TRIO domain protein Cowc_CAOG_07825T0 PRIM2 DNA primase large Cowc_CAOG_07901T0 Solute carrier family 38 member Cowc_CAOG_07959T0 HIST2H2AB histone cluster 2, H2ab Cowc_CAOG_08077T0 MSH3 mutS homolog 3 (E. coli) Cowc_CAOG_01199T0 CCNB3 cyclin B3 Cowc_CAOG_01465T0 NAD dependent epimerase/dehydratase family Cowc_CAOG_01557T0 STAG1 Stromal antigen Cowc_CAOG_01569T0 Protein kinase domain Cowc_CAOG_01720T0 Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (By similarity) Cowc_CAOG_01758T0 ASF1 ASF1 like histone chaperone Cowc_CAOG_01818T0 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling Cowc_CAOG_01945T0 DHRSX Dehydrogenase reductase (SDR family) X-linked Cowc_CAOG_01975T0 Kinesin family member Cowc_CAOG_01984T0 SMC3 Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement Cowc_CAOG_02250T0 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling Cowc_CAOG_02298T0 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling Cowc_CAOG_09556T0 RRM1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) Cowc_CAOG_02657T0 DAAM1 dishevelled associated activator of morphogenesis 1 Cowc_CAOG_02831T0 Domain of unknown function (DUF1943) Cowc_CAOG_03220T0 KIF22 kinesin family member 22 Cowc_CAOG_03970T0 Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism (By similarity) Cowc_CAOG_04238T0 ARHGAP19 Rho GTPase activating protein 19 Cowc_CAOG_04719T0 CCNA2 Cyclin, C-terminal domain Cowc_CAOG_04765T0 Inherit from KOG: MAK16 homolog (S. cerevisiae) Cowc_CAOG_04846T0 NOLC1 nucleolar and coiled-body phosphoprotein 1 Cowc_CAOG_05068T0 PAV KISc Cowc_CAOG_05121T0 PCNA This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand (By similarity) Cowc_CAOG_05377T0