Beyond the MHC: A canine model of dermatomyositis shows a complex pattern of genetic risk involving novel loci
Manhattan plots of DMS GWASs in two breeds.
(A) Collies: 31 cases and 23 controls. (B) Shetland sheepdogs: 66 cases and 45 controls. The –log10P-values (y-axis) for 98,520 Illumina SNPs are plotted against chromosome position (x-axis). The threshold for Bonferroni significance is shown as a black horizontal line. The P-value and position (canFam3) of the lead SNPs are reported.