Comparison of Methods to Account for Relatedness in Genome-Wide Association Studies with Family-Based Data
The points marked in red denote the confirmed significant region from Fakiola et al. (2013). FLMM_E = FaST-LMM using exact calculation, MQLS1972 = MQLS using 1972 genotyped individuals, RT1972 = ROADTRIPS using 1972 genotyped individuals, FBATaff = FBAT using transmissions to affecteds only, FBATboth = FBAT using transmissions to both affecteds and unaffecteds. Results from all other LMM methods were indistinguishable from FLMM_E and so are not shown.