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A General Approach for Haplotype Phasing across the Full Spectrum of Relatedness

Figure 7

Recombination detection accuracy in uninformative duos simulated from chromosome X data in the Val Borbera cohort.

The green values are for a cohort with nominally unrelated individuals and the orange values are for a cohort that has been filtered such that no individuals are closely related (). Left: The ROC curves for recombination detection in uninformative duos for our duo HMM using the SHAPEIT2 haplotypes. Right: The average number of correct detections against the average posterior probability. Setting a high probability threshold ensures a very low false discovery rate.

Figure 7