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Drosophila Functional Elements Are Embedded in Structurally Constrained Sequences

Figure 4

Enrichment of microsatellites in the proximity of conserved elements.

A–E) Shown in black are distributions of enrichment (log2 of the ratio between the frequency at a certain distance from a CE and the global average) computed for various tandem repeats and motifs around CEs (black). Shown in red are similar statistics, but this time normalized according to the nucleotide compositions of the corresponding distance around CEs (i.e. dividing the frequency of each k-mer by the product of its nucleotides' frequencies). The data suggest remarkably uniform enrichment of tandem repeats around CEs.

Figure 4