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The Non-Flagellar Type III Secretion System Evolved from the Bacterial Flagellum and Diversified into Host-Cell Adapted Systems

Figure 4

Concatenate phylogeny of the core NF-T3SS proteins with flagellar homologs.

The eight individual gene trees are displayed in Figure S3. The large monophyletic clades highlighted by different colors correspond to the NF-T3SS families (names in bold, see Text S2). Colored circles indicate the bootstrap support of these families and of the relationships between them. The “Ecology/Host” panel indicates the predominant bacterium/eukaryote associations for each family (see main text and Figure S4). The external branch indicates the position of the flagellum sequences and was inferred with the “rooted” dataset (“rooted” tree is in Figure S5). “Chlamy” stands for Chlamydiales, “Desulfo” for Desulfovibrionales, “Myxo” for Myxococcales, and “Rhizo” for Rhizobiales. The scale of the tree is given in substitutions per site.

Figure 4

doi: https://doi.org/10.1371/journal.pgen.1002983.g004