A Novel Unstable Duplication Upstream of HAS2 Predisposes to a Breed-Defining Skin Phenotype and a Periodic Fever Syndrome in Chinese Shar-Pei Dogs
Figure 5
Expression analysis reveals a trend of increased HAS2 and HAS2as expression with copy number.
Expression levels were measured in dermal fibroblasts that were cultured from individual Shar-Pei skin biopsies. The individual with the lowest copy number (CNV = 5) was used to calibrate each assay.