Endogenous Viral Elements in Animal Genomes
(a) The primate clade marked by an asterisk in the phylogeny shown in Figure 6 is shown in greater detail here, with the number of stop codons in the EBLN-1 locus indicated for seven species. Orthology across these species indicates that EBLN-1 predates the divergence of these species 54 million years ago . Monte Carlo simulations in which a consensus EBLN sequence was allowed to neutrally evolve at the primate neutral rate for this length of time showed that the average number of stop codons expected after this time is fifteen. (b) The distribution of the number of stop codons from 100,000 simulation replicates. Confidence intervals are indicated.