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Open Access
Peer-reviewed
Research Article
Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling
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Na Liu ,
Contributed equally to this work with: Na Liu, Yu Yin, Haiying Wang
Roles Investigation, Writing – original draft
Affiliations State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China, Key Laboratory of Bioactive Materials, Ministry of Education, Department of Cell Biology and Genetics, College of Life Sciences, Nankai University, Tianjin, China, School of Medicine, Nankai University, Tianjin, China
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Yu Yin ,
Contributed equally to this work with: Na Liu, Yu Yin, Haiying Wang
Roles Data curation, Investigation, Methodology
Affiliations State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China, Yunnan Key Laboratory of Primate Biomedical Research; Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, China
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Haiying Wang ,
Contributed equally to this work with: Na Liu, Yu Yin, Haiying Wang
Roles Investigation, Validation
Affiliation State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China
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Zhongcheng Zhou,
Roles Investigation, Methodology
Affiliation State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China
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Xiaoyan Sheng,
Roles Investigation, Methodology
Affiliation State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China
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Haifeng Fu,
Roles Investigation, Methodology
Affiliation State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China
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Renpeng Guo,
Roles Investigation
Affiliation State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China
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Hua Wang,
Roles Investigation, Methodology
Affiliation State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China
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Jiao Yang,
Roles Investigation
Affiliation State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China
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Peng Gong,
Roles Investigation
Affiliation State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China
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Wen Ning,
Roles Resources
Affiliation State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China
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Zhenyu Ju,
Roles Resources, Writing – review & editing
Affiliation Key Laboratory of Regenerative Medicine of Ministry of Education, Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China
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Yifei Liu ,
Roles Methodology, Resources, Validation, Writing – review & editing
* E-mail: yifei.liu@yale.edu (YL); liulin@nankai.edu.cn (LL)
Affiliation Yale Fertility Center and Department of OB/GYN, Yale University School of Medicine, New Haven, CT, United States of America
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Lin Liu
Roles Conceptualization, Investigation, Supervision, Writing – review & editing
* E-mail: yifei.liu@yale.edu (YL); liulin@nankai.edu.cn (LL)
Affiliations State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, China, Key Laboratory of Bioactive Materials, Ministry of Education, Department of Cell Biology and Genetics, College of Life Sciences, Nankai University, Tianjin, China
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Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling
- Na Liu,
- Yu Yin,
- Haiying Wang,
- Zhongcheng Zhou,
- Xiaoyan Sheng,
- Haifeng Fu,
- Renpeng Guo,
- Hua Wang,
- Jiao Yang,
- Peng Gong
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- Published: September 13, 2019
- https://doi.org/10.1371/journal.pgen.1008368