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Open Access
Peer-reviewed
Research Article
Comprehensive Analysis of Transcriptome Variation Uncovers Known and Novel Driver Events in T-Cell Acute Lymphoblastic Leukemia
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Zeynep Kalender Atak ,
Contributed equally to this work with: Zeynep Kalender Atak, Valentina Gianfelici, Gert Hulselmans, Kim De Keersmaecker
Affiliation Laboratory of Computational Biology, Center for Human Genetics, KU Leuven, Leuven, Belgium
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Valentina Gianfelici ,
Contributed equally to this work with: Zeynep Kalender Atak, Valentina Gianfelici, Gert Hulselmans, Kim De Keersmaecker
Affiliations Laboratory for the Molecular Biology of Leukemia, Center for Human Genetics, KU Leuven and Center for the Biology of Disease, VIB, Leuven, Belgium, Division of Hematology, Department of Cellular Biotechnologies and Hematology, ‘Sapienza’ University of Rome, Rome, Italy
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Gert Hulselmans ,
Contributed equally to this work with: Zeynep Kalender Atak, Valentina Gianfelici, Gert Hulselmans, Kim De Keersmaecker
Affiliation Laboratory of Computational Biology, Center for Human Genetics, KU Leuven, Leuven, Belgium
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Kim De Keersmaecker ,
Contributed equally to this work with: Zeynep Kalender Atak, Valentina Gianfelici, Gert Hulselmans, Kim De Keersmaecker
Affiliation Laboratory for the Molecular Biology of Leukemia, Center for Human Genetics, KU Leuven and Center for the Biology of Disease, VIB, Leuven, Belgium
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Arun George Devasia,
Affiliations Laboratory of Computational Biology, Center for Human Genetics, KU Leuven, Leuven, Belgium, Laboratory for the Molecular Biology of Leukemia, Center for Human Genetics, KU Leuven and Center for the Biology of Disease, VIB, Leuven, Belgium
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Ellen Geerdens,
Affiliation Laboratory for the Molecular Biology of Leukemia, Center for Human Genetics, KU Leuven and Center for the Biology of Disease, VIB, Leuven, Belgium
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Nicole Mentens,
Affiliation Laboratory for the Molecular Biology of Leukemia, Center for Human Genetics, KU Leuven and Center for the Biology of Disease, VIB, Leuven, Belgium
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Sabina Chiaretti,
Affiliation Division of Hematology, Department of Cellular Biotechnologies and Hematology, ‘Sapienza’ University of Rome, Rome, Italy
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Kaat Durinck,
Affiliation Center for Medical Genetics, Ghent University, Ghent, Belgium
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Anne Uyttebroeck,
Affiliation Pediatric Hemato-Oncology, University Hospitals Leuven, Leuven, Belgium
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Peter Vandenberghe,
Affiliation Laboratory for the Molecular Biology of Leukemia, Center for Human Genetics, KU Leuven and Center for the Biology of Disease, VIB, Leuven, Belgium
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Iwona Wlodarska,
Affiliation Laboratory for the Molecular Biology of Leukemia, Center for Human Genetics, KU Leuven and Center for the Biology of Disease, VIB, Leuven, Belgium
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Jacqueline Cloos,
Affiliation Pediatric Oncology/Hematology and Hematology, VU Medical Center, Amsterdam, The Netherlands
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Robin Foà,
Affiliation Division of Hematology, Department of Cellular Biotechnologies and Hematology, ‘Sapienza’ University of Rome, Rome, Italy
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Frank Speleman,
Affiliation Center for Medical Genetics, Ghent University, Ghent, Belgium
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Jan Cools ,
* E-mail: jan.cools@cme.vib-kuleuven.be (JC); stein.aerts@med.kuleuven.be (SA)
Affiliation Laboratory for the Molecular Biology of Leukemia, Center for Human Genetics, KU Leuven and Center for the Biology of Disease, VIB, Leuven, Belgium
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Stein Aerts
* E-mail: jan.cools@cme.vib-kuleuven.be (JC); stein.aerts@med.kuleuven.be (SA)
Affiliation Laboratory of Computational Biology, Center for Human Genetics, KU Leuven, Leuven, Belgium
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Comprehensive Analysis of Transcriptome Variation Uncovers Known and Novel Driver Events in T-Cell Acute Lymphoblastic Leukemia
- Zeynep Kalender Atak,
- Valentina Gianfelici,
- Gert Hulselmans,
- Kim De Keersmaecker,
- Arun George Devasia,
- Ellen Geerdens,
- Nicole Mentens,
- Sabina Chiaretti,
- Kaat Durinck,
- Anne Uyttebroeck
- Published: December 19, 2013
- https://doi.org/10.1371/journal.pgen.1003997