Age-Dependent Brain Gene Expression and Copy Number Anomalies in Autism Suggest Distinct Pathological Processes at Young Versus Mature Ages

• Maggie L. Chow ,

  Contributed equally to this work with: Maggie L. Chow, Tiziano Pramparo

  Affiliation Department of Neuroscience, NIH–UCSD Autism Center of Excellence, School of Medicine, University of California San Diego, La Jolla, California, United States of America

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• Tiziano Pramparo ,

  Contributed equally to this work with: Maggie L. Chow, Tiziano Pramparo

  Affiliations Department of Neuroscience, NIH–UCSD Autism Center of Excellence, School of Medicine, University of California San Diego, La Jolla, California, United States of America, Division of Medical Genetics, Department of Pediatrics and Institute of Human Genetics, School of Medicine, University of California San Francisco, San Francisco, California, United States of America

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• Mary E. Winn,

  Affiliations Scripps Genomic Medicine and The Scripps Translational Sciences Institute (STSI), La Jolla, California, United States of America, Graduate Program in Biomedical Sciences, Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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• Cynthia Carter Barnes,

  Affiliation Department of Neuroscience, NIH–UCSD Autism Center of Excellence, School of Medicine, University of California San Diego, La Jolla, California, United States of America

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• Hai-Ri Li,

  Affiliation Department of Cellular and Molecular Medicine, School of Medicine, University of California San Diego, La Jolla, California, United States of America

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• Lauren Weiss,

  Affiliation Department of Psychiatry, School of Medicine, University of California San Francisco, San Francisco, California, United States of America

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• Jian-Bing Fan,

  Affiliation Illumina, San Diego, California, United States of America

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• Sarah Murray,

  Affiliation Scripps Genomic Medicine and The Scripps Translational Sciences Institute (STSI), La Jolla, California, United States of America

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• Craig April,

  Affiliation Illumina, San Diego, California, United States of America

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• Haim Belinson,

  Affiliation Division of Medical Genetics, Department of Pediatrics and Institute of Human Genetics, School of Medicine, University of California San Francisco, San Francisco, California, United States of America

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• Xiang-Dong Fu ,

  ¶These authors were joint senior authors on this work.

  Affiliation Department of Cellular and Molecular Medicine, School of Medicine, University of California San Diego, La Jolla, California, United States of America

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• Anthony Wynshaw-Boris ,

  ¶These authors were joint senior authors on this work.

  Affiliation Division of Medical Genetics, Department of Pediatrics and Institute of Human Genetics, School of Medicine, University of California San Francisco, San Francisco, California, United States of America

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• Nicholas J. Schork ,

  * E-mail: nschork@scripps.edu (NJS); ecourchesne@ucsd.edu (EC)

  ¶These authors were joint senior authors on this work.

  Affiliation Scripps Genomic Medicine and The Scripps Translational Sciences Institute (STSI), La Jolla, California, United States of America

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• Eric Courchesne

  * E-mail: nschork@scripps.edu (NJS); ecourchesne@ucsd.edu (EC)

  ¶These authors were joint senior authors on this work.

  Affiliation Department of Neuroscience, NIH–UCSD Autism Center of Excellence, School of Medicine, University of California San Diego, La Jolla, California, United States of America

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