SNPs Associated with Cerebrospinal Fluid Phospho-Tau Levels Influence Rate of Decline in Alzheimer's Disease

• Carlos Cruchaga ,

  Contributed equally to this work with: Carlos Cruchaga, John S. K. Kauwe

  * E-mail: cruchagc@psychiatry.wustl.edu

  Affiliations Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America, The Hope Center Program on Protein Aggregation and Neurodegeneration (HPAN), Washington University School of Medicine, St. Louis, Missouri, United States of America

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• John S. K. Kauwe ,

  Contributed equally to this work with: Carlos Cruchaga, John S. K. Kauwe

  Affiliation Department of Biology, Brigham Young University, Provo, Utah, United States of America

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• Kevin Mayo,

  Affiliations Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America, The Hope Center Program on Protein Aggregation and Neurodegeneration (HPAN), Washington University School of Medicine, St. Louis, Missouri, United States of America

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• Noah Spiegel,

  Affiliations Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America, The Hope Center Program on Protein Aggregation and Neurodegeneration (HPAN), Washington University School of Medicine, St. Louis, Missouri, United States of America

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• Sarah Bertelsen,

  Affiliation Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America

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• Petra Nowotny,

  Affiliations Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America, The Hope Center Program on Protein Aggregation and Neurodegeneration (HPAN), Washington University School of Medicine, St. Louis, Missouri, United States of America

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• Aarti R. Shah,

  Affiliations The Hope Center Program on Protein Aggregation and Neurodegeneration (HPAN), Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, United States of America

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• Richard Abraham,

  Affiliation Department of Neurology, University of Washington School of Medicine, Seattle, Washington, United States of America

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• Paul Hollingworth,

  Affiliation Department of Psychological Medicine, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, United Kingdom

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• Denise Harold,

  Affiliation Department of Psychological Medicine, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, United Kingdom

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• Michael M. Owen,

  Affiliation Department of Psychological Medicine, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, United Kingdom

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• Julie Williams,

  Affiliation Department of Psychological Medicine, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, United Kingdom

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• Simon Lovestone,

  Affiliation Kings College, London, United Kingdom

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• Elaine R. Peskind,

  Affiliations Departments of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, United States of America, Veterans Affairs Northwest Network Mental Illness Research, Education, and Clinical Center, Seattle, Washington, United States of America

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• Ge Li,

  Affiliations Departments of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, United States of America, Veterans Affairs Northwest Network Mental Illness Research, Education, and Clinical Center, Seattle, Washington, United States of America

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• James B. Leverenz,

  Affiliations Departments of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, United States of America, Veterans Affairs Northwest Network Mental Illness Research, Education, and Clinical Center, Seattle, Washington, United States of America, Department of Neurology, University of Washington School of Medicine, Seattle, Washington, United States of America

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• Douglas Galasko,

  Affiliation Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America

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• The Alzheimer's Disease Neuroimaging Initiative ,

  ¶A complete listing of the investigators for the Alzheimer's Disease Neuroimaging Initiative is provided in the Acknowledgments.

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• John C. Morris,

  Affiliations Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Kings College, London, United Kingdom

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• Anne M. Fagan,

  Affiliations The Hope Center Program on Protein Aggregation and Neurodegeneration (HPAN), Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, Missouri, United States of America

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• David M. Holtzman,

  Affiliations The Hope Center Program on Protein Aggregation and Neurodegeneration (HPAN), Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, Missouri, United States of America

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•  [ ... ],
• Alison M. Goate

  Affiliations Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America, The Hope Center Program on Protein Aggregation and Neurodegeneration (HPAN), Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, Missouri, United States of America

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