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Rare genetic variation at transcription factor binding sites modulates local DNA methylation profiles
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Alejandro Martin-Trujillo,
Roles Conceptualization, Formal analysis, Funding acquisition, Writing – original draft, Writing – review & editing
Affiliation The Mindich Child Health and Development Institute and Department of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
⨯ -
Nihir Patel,
Roles Conceptualization, Formal analysis, Writing – review & editing
Affiliation The Mindich Child Health and Development Institute and Department of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
⨯ -
Felix Richter,
Roles Conceptualization, Formal analysis, Writing – review & editing
Affiliation The Mindich Child Health and Development Institute and Department of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
⨯ - Bharati Jadhav,
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Paras Garg,
Roles Formal analysis, Writing – review & editing
Affiliation The Mindich Child Health and Development Institute and Department of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Sarah U. Morton,
Roles Formal analysis, Resources, Writing – review & editing
Affiliation Department of Newborn Medicine, Boston Children’s Hospital, Boston, Massachusetts, United States of America
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David M. McKean,
Roles Formal analysis, Writing – review & editing
Affiliation Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, United States of America
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Steven R. DePalma,
Roles Resources, Writing – review & editing
Affiliations Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America, Howard Hughes Medical Institute, Harvard University, Boston, Massachusetts, United States of America
⨯ - Elizabeth Goldmuntz,
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Dorota Gruber,
Roles Resources, Writing – review & editing
Affiliation Department of Pediatrics, Cohen Children’s Medical Center, Northwell Health, New Hyde Park, NY, Unites States of America
⨯ - Richard Kim,
- Jane W. Newburger,
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George A. Porter Jr.,
Roles Resources, Writing – review & editing
Affiliation Department of Pediatrics, University of Rochester Medical Center, Rochester, NY, United States of America
⨯ - Alessandro Giardini,
- Daniel Bernstein,
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Martin Tristani-Firouzi,
Roles Resources, Writing – review & editing
Affiliation Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, United States of America
⨯ - Jonathan G. Seidman,
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Christine E. Seidman,
Roles Resources, Writing – review & editing
Affiliations Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America, Howard Hughes Medical Institute, Harvard University, Boston, Massachusetts, United States of America
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Wendy K. Chung,
Roles Resources, Writing – review & editing
Affiliation Departments of Pediatrics and Medicine, Columbia University, New York, NY, United States of America
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Bruce D. Gelb,
Roles Conceptualization, Resources, Writing – review & editing
Affiliations The Mindich Child Health and Development Institute and Department of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, United States of America
⨯ - [ ... ],
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Andrew J. Sharp
Roles Conceptualization, Funding acquisition, Resources, Writing – original draft, Writing – review & editing
* E-mail: andrew.sharp@mssm.edu
Affiliations The Mindich Child Health and Development Institute and Department of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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https://orcid.org/0000-0003-1089-3941
Rare genetic variation at transcription factor binding sites modulates local DNA methylation profiles
- Alejandro Martin-Trujillo,
- Nihir Patel,
- Felix Richter,
- Bharati Jadhav,
- Paras Garg,
- Sarah U. Morton,
- David M. McKean,
- Steven R. DePalma,
- Elizabeth Goldmuntz,
- Dorota Gruber
- Published: November 20, 2020
- https://doi.org/10.1371/journal.pgen.1009189