Deep Sequencing of Plant and Animal DNA Contained within Traditional Chinese Medicines Reveals Legality Issues and Health Safety Concerns

Megan L. Coghlan; James Haile; Jayne Houston; Dáithí C. Murray; Nicole E. White; Paula Moolhuijzen; Matthew I. Bellgard; Michael Bunce

doi:10.1371/journal.pgen.1002657

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Open Access

Peer-reviewed

Research Article

Deep Sequencing of Plant and Animal DNA Contained within Traditional Chinese Medicines Reveals Legality Issues and Health Safety Concerns

Megan L. Coghlan,

Affiliation Australian Wildlife Forensic Services and Ancient DNA Laboratory, School of Biological Sciences and Biotechnology, Murdoch University, Murdoch, Australia
⨯
James Haile,

Affiliation Australian Wildlife Forensic Services and Ancient DNA Laboratory, School of Biological Sciences and Biotechnology, Murdoch University, Murdoch, Australia
⨯
Jayne Houston,

Affiliation Australian Wildlife Forensic Services and Ancient DNA Laboratory, School of Biological Sciences and Biotechnology, Murdoch University, Murdoch, Australia
⨯
Dáithí C. Murray,

Affiliation Australian Wildlife Forensic Services and Ancient DNA Laboratory, School of Biological Sciences and Biotechnology, Murdoch University, Murdoch, Australia
⨯
Nicole E. White,

Affiliation Australian Wildlife Forensic Services and Ancient DNA Laboratory, School of Biological Sciences and Biotechnology, Murdoch University, Murdoch, Australia
⨯
Paula Moolhuijzen,

Affiliation Centre for Comparative Genomics, Murdoch University, Murdoch, Australia
⨯
Matthew I. Bellgard,

Affiliation Centre for Comparative Genomics, Murdoch University, Murdoch, Australia
⨯
Michael Bunce

* E-mail: m.bunce@murdoch.edu.au

Affiliation Australian Wildlife Forensic Services and Ancient DNA Laboratory, School of Biological Sciences and Biotechnology, Murdoch University, Murdoch, Australia
⨯

Deep Sequencing of Plant and Animal DNA Contained within Traditional Chinese Medicines Reveals Legality Issues and Health Safety Concerns

Megan L. Coghlan,
James Haile,
Jayne Houston,
Dáithí C. Murray,
Nicole E. White,
Paula Moolhuijzen,
Matthew I. Bellgard,
Michael Bunce

Published: April 12, 2012
https://doi.org/10.1371/journal.pgen.1002657

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Revolutionize CTM

Posted by zkzlzx on 07 May 2012 at 08:12 GMT

As for the toxic plants in the CTM, I think there are three sources: a, the toxic plants are mixed in the raw material by accident during collection in the field because of similar appearences. b, the elements of toxic plants, as contents of other medicine, find the way to the target medicine by, for examplem, powder in the air, we can call it "contamination", and even minor amouts can be detected by next-generation sequencing technology. c, the toxic plants may be just useful components of the medicine, but they are kept for secrete for commercial purpose.

No competing interests declared.

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Deep Sequencing of Plant and Animal DNA Contained within Traditional Chinese Medicines Reveals Legality Issues and Health Safety Concerns

Deep Sequencing of Plant and Animal DNA Contained within Traditional Chinese Medicines Reveals Legality Issues and Health Safety Concerns

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Revolutionize CTM

Posted by zkzlzx on 07 May 2012 at 08:12 GMT