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Posted by PLOS_Genetics on 20 Mar 2009 at 10:04 GMT

We have demonstrated here that complex animal regulatory sequences can tolerate nearly complete rearrangement of their transcription factor binding sites without appreciably altering their transcriptional output.

- A Closer Look at the eve Stripe 2 Enhancers of Drosophila and Themira (

- A Careful Look at Binding Site Reorganization in the even-skipped Enhancers of Drosophila and Sepsids (

No competing interests declared.