About the Authors

Steffen Grampp

Contributed equally to this work with: Steffen Grampp, Virginia Schmid, Rafik Salama

Roles Data curation, Formal analysis, Investigation

Affiliation Department of Nephrology and Hypertension, Universitätsklinikum Erlangen und Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany

Virginia Schmid

Contributed equally to this work with: Steffen Grampp, Virginia Schmid, Rafik Salama

Roles Data curation, Formal analysis

Affiliation NDM Research Building, University of Oxford, Old Road Campus, Headington, Oxford, United Kingdom

Rafik Salama

Contributed equally to this work with: Steffen Grampp, Virginia Schmid, Rafik Salama

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Visualization

Affiliation NDM Research Building, University of Oxford, Old Road Campus, Headington, Oxford, United Kingdom

Victoria Lauer

Roles Formal analysis, Investigation, Methodology

Affiliation Department of Nephrology and Hypertension, Universitätsklinikum Erlangen und Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany

Franziska Kranz

Roles Methodology, Software, Visualization

Affiliations Department of Nephrology and Hypertension, Universitätsklinikum Erlangen und Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany, Department of Computer Science 9, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany

James L. Platt

Roles Data curation, Formal analysis, Investigation, Methodology, Visualization

Affiliation NDM Research Building, University of Oxford, Old Road Campus, Headington, Oxford, United Kingdom

James Smythies

Roles Data curation, Formal analysis, Investigation, Methodology, Visualization

Affiliation NDM Research Building, University of Oxford, Old Road Campus, Headington, Oxford, United Kingdom

Hani Choudhry

Roles Data curation, Investigation

Affiliation Department of Biochemistry, Faculty of Science, Center of Innovation in Personalized Medicine, King Fahd Center for Medical Research, King Abdulaziz University, Jeddah, Saudi Arabia

Margarete Goppelt-Struebe

Roles Methodology, Resources

Affiliation Department of Nephrology and Hypertension, Universitätsklinikum Erlangen und Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany

Peter J. Ratcliffe

Roles Conceptualization, Funding acquisition, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

peter.ratcliffe@ndm.ox.ac.uk (PJR); drmole@well.ox.ac.uk (DRM); Johannes.schoedel@uk-erlangen.de (JS)

‡ PJR, DRM, and JS also contributed equally to this work.

Affiliation NDM Research Building, University of Oxford, Old Road Campus, Headington, Oxford, United Kingdom

David R. Mole

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

peter.ratcliffe@ndm.ox.ac.uk (PJR); drmole@well.ox.ac.uk (DRM); Johannes.schoedel@uk-erlangen.de (JS)

‡ PJR, DRM, and JS also contributed equally to this work.

Affiliation NDM Research Building, University of Oxford, Old Road Campus, Headington, Oxford, United Kingdom

Johannes Schödel

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

peter.ratcliffe@ndm.ox.ac.uk (PJR); drmole@well.ox.ac.uk (DRM); Johannes.schoedel@uk-erlangen.de (JS)

‡ PJR, DRM, and JS also contributed equally to this work.

Affiliation Department of Nephrology and Hypertension, Universitätsklinikum Erlangen und Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany

Competing Interests

PJR is a scientific co-founder of ReOx Ltd., a company, which is developing inhibitors of the HIF hydroxylase enzymes. The other authors declare no competing interest.