About the Authors

Hao Hu

Affiliation Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Nayia Petousi

Affiliation Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

Gustavo Glusman

Affiliation Institute for Systems Biology, Seattle, Washington, United States of America

Yao Yu

Affiliation Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Ryan Bohlender

Affiliation Department of Anthropology, University of Utah, Salt Lake City, Utah, United States of America

Tsewang Tashi

Affiliation Department of Medicine, University of Utah School of Medicine and George E. Wahlin Veterans Administration Medical Center, Salt Lake City, Utah, United States of America

Jonathan M. Downie

Affiliation Department of Human Genetics, University of Utah, Salt Lake City, Utah, United States of America

Jared C. Roach

Affiliation Institute for Systems Biology, Seattle, Washington, United States of America

Amy M. Cole

Affiliation Department of Molecular and Cellular Therapeutics, The Royal College of Surgeons in Ireland, Dublin, Ireland

Felipe R. Lorenzo

Affiliation Department of Medicine, University of Utah School of Medicine and George E. Wahlin Veterans Administration Medical Center, Salt Lake City, Utah, United States of America

Alan R. Rogers

Affiliation Department of Anthropology, University of Utah, Salt Lake City, Utah, United States of America

Mary E. Brunkow

Affiliation Institute for Systems Biology, Seattle, Washington, United States of America

Gianpiero Cavalleri

Affiliation Department of Molecular and Cellular Therapeutics, The Royal College of Surgeons in Ireland, Dublin, Ireland

Leroy Hood

Affiliation Institute for Systems Biology, Seattle, Washington, United States of America

Sama M. Alpatty

Affiliation Skaggs School of Pharmacy and Pharmaceutical Science, UC San Diego, La Jolla, California, United States of America

Josef T. Prchal

Contributed equally to this work with: Josef T. Prchal, Lynn B. Jorde, Peter A. Robbins, Tatum S. Simonson, Chad D. Huff

Affiliations Department of Medicine, University of Utah School of Medicine and George E. Wahlin Veterans Administration Medical Center, Salt Lake City, Utah, United States of America, Department of Human Genetics, University of Utah, Salt Lake City, Utah, United States of America

Lynn B. Jorde

Contributed equally to this work with: Josef T. Prchal, Lynn B. Jorde, Peter A. Robbins, Tatum S. Simonson, Chad D. Huff

Affiliation Department of Human Genetics, University of Utah, Salt Lake City, Utah, United States of America

Peter A. Robbins

Contributed equally to this work with: Josef T. Prchal, Lynn B. Jorde, Peter A. Robbins, Tatum S. Simonson, Chad D. Huff

Affiliation Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom

Tatum S. Simonson

Contributed equally to this work with: Josef T. Prchal, Lynn B. Jorde, Peter A. Robbins, Tatum S. Simonson, Chad D. Huff

Affiliation Department of Medicine, Division of Physiology, University of California San Diego, La Jolla, California, United States of America

Chad D. Huff

Contributed equally to this work with: Josef T. Prchal, Lynn B. Jorde, Peter A. Robbins, Tatum S. Simonson, Chad D. Huff

chad@hufflab.org

Affiliation Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceptualization: CDH TSS JTP LBJ JCR PAR. Data curation: HH CDH. Formal analysis: HH GG YY RB ARR JMD CDH. Investigation: CDH HH TSS LBJ JTP GC PAR GG YY RB JMD JCR AMC ARR. Methodology: HH GG YY RB ARR JMD CDH. Project administration: CDH TSS JTP LBJ JCR PAR. Resources: PAR TSS JCR NP GG TT FRL LH MEB SMA LBJ. Software: HH YY RB. Supervision: CDH TSS JTP LBJ JCR PAR. Writing – original draft: HH CDH TSS JTP LBJ NP YY RB. Writing – review & editing: HH CDH TSS JTP JCR LBJ NP GG YY RB TT JMD AMC FRL ARR MEB GC PAR.