About the Authors

Antonio F. Di Narzo

Affiliations Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Shannon E. Telesco

Affiliation Janssen R&D, LLC, Spring House, Pennsylvania, United States of America

Carrie Brodmerkel

Affiliation Janssen R&D, LLC, Spring House, Pennsylvania, United States of America

Carmen Argmann

Affiliations Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Lauren A. Peters

Affiliations Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Katherine Li

Affiliation Janssen R&D, LLC, Spring House, Pennsylvania, United States of America

Brian Kidd

Affiliations Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Joel Dudley

Affiliations Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Judy Cho

Affiliations Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Eric E. Schadt

Affiliations Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Andrew Kasarskis

Affiliations Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Radu Dobrin

RDobrin@ITS.JNJ.com (RD); ke.hao@mssm.edu (KH)

Affiliation Janssen R&D, LLC, Spring House, Pennsylvania, United States of America

Ke Hao

RDobrin@ITS.JNJ.com (RD); ke.hao@mssm.edu (KH)

Affiliations Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Competing Interests

We have read the journal's policy and the authors of this manuscript have the following competing interests. The following authors: SET, CB, KL and RD are paid employees of Janssen R&D LLC. The work is partially supported by Janssen R&D LLC.

Author Contributions

Conceptualization: AFDN SET CB JC EES AK RD KH. Data curation: AFDN SET CB JC EES AK RD KH. Formal analysis: AFDN LAP CA KL SET CB BK KH. Writing – original draft: AFDN SET CB LAP CA AK JD JC KL RD KH.