About the Authors

Fiona Semple

Affiliations MRC Centre for Inflammation Research, University of Edinburgh, Queen’s Medical Research Institute (QMRI), Edinburgh, United Kingdom, MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Edinburgh, United Kingdom

Heather MacPherson

Affiliation MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Edinburgh, United Kingdom

Sheila Webb

Affiliation MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Edinburgh, United Kingdom

Fiona Kilanowski

Affiliation MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Edinburgh, United Kingdom

Laura Lettice

Affiliation MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Edinburgh, United Kingdom

Sarah L. McGlasson

Affiliation MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Edinburgh, United Kingdom

Ann P. Wheeler

Affiliation MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Edinburgh, United Kingdom

Valerie Chen

Affiliation Department of Chemistry and Biochemistry, University of California, Santa Cruz, Santa Cruz, California, United States of America

Glenn L. Millhauser

Affiliation Department of Chemistry and Biochemistry, University of California, Santa Cruz, Santa Cruz, California, United States of America

Lauren Melrose

Affiliation MRC Centre for Inflammation Research, University of Edinburgh, Queen’s Medical Research Institute (QMRI), Edinburgh, United Kingdom

Donald J. Davidson

Affiliation MRC Centre for Inflammation Research, University of Edinburgh, Queen’s Medical Research Institute (QMRI), Edinburgh, United Kingdom

Julia R. Dorin

Julia.dorin@ed.ac.uk

Affiliations MRC Centre for Inflammation Research, University of Edinburgh, Queen’s Medical Research Institute (QMRI), Edinburgh, United Kingdom, MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Edinburgh, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JRD FS HM DJD. Performed the experiments: FS HM SW FK LL SLM VC LM. Analyzed the data: FS HM APW GLM DJD JRD. Contributed reagents/materials/analysis tools: VC GLM. Wrote the paper: FS APW DJD JRD.