Rrp12 and the Exportin Crm1 Participate in Late Assembly Events in the Nucleolus during 40S Ribosomal Subunit Biogenesis

Giulia Moriggi; Blanca Nieto; Mercedes Dosil

doi:10.1371/journal.pgen.1004836

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Peer-reviewed

Research Article

Rrp12 and the Exportin Crm1 Participate in Late Assembly Events in the Nucleolus during 40S Ribosomal Subunit Biogenesis

Giulia Moriggi,

Affiliation Centro de Investigación del Cáncer and Instituto de Biología Molecular y Celular del Cáncer (IBMCC), CSIC-University of Salamanca, Salamanca, Spain
⨯
Blanca Nieto,

Affiliation Centro de Investigación del Cáncer and Instituto de Biología Molecular y Celular del Cáncer (IBMCC), CSIC-University of Salamanca, Salamanca, Spain
⨯
Mercedes Dosil

* E-mail: mdosil@usal.es

Affiliations Centro de Investigación del Cáncer and Instituto de Biología Molecular y Celular del Cáncer (IBMCC), CSIC-University of Salamanca, Salamanca, Spain, Departamento de Bioquímica y Biología Molecular, University of Salamanca, Salamanca, Spain
⨯

Rrp12 and the Exportin Crm1 Participate in Late Assembly Events in the Nucleolus during 40S Ribosomal Subunit Biogenesis

Giulia Moriggi,
Blanca Nieto,
Mercedes Dosil

Published: December 4, 2014
https://doi.org/10.1371/journal.pgen.1004836

About the Authors

Giulia Moriggi

Affiliation Centro de Investigación del Cáncer and Instituto de Biología Molecular y Celular del Cáncer (IBMCC), CSIC-University of Salamanca, Salamanca, Spain

Blanca Nieto

Affiliation Centro de Investigación del Cáncer and Instituto de Biología Molecular y Celular del Cáncer (IBMCC), CSIC-University of Salamanca, Salamanca, Spain

Mercedes Dosil

* E-mail: mdosil@usal.es

Affiliations Centro de Investigación del Cáncer and Instituto de Biología Molecular y Celular del Cáncer (IBMCC), CSIC-University of Salamanca, Salamanca, Spain, Departamento de Bioquímica y Biología Molecular, University of Salamanca, Salamanca, Spain

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GM MD. Performed the experiments: GM BN. Analyzed the data: GM MD. Wrote the paper: MD.

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Northern blot
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Immunoprecipitation
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Ribosomal RNA
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Co-immunoprecipitation
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Nucleolus
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Sedimentation
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Yeast
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Cytoplasm
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