Fifteen Years Later: Hard and Soft Selection Sweeps Confirm a Large Population Number for HIV In Vivo

Igor M. Rouzine; John M. Coffin; Leor S. Weinberger

doi:10.1371/journal.pgen.1004179

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Fifteen Years Later: Hard and Soft Selection Sweeps Confirm a Large Population Number for HIV In Vivo

Igor M. Rouzine ,

* E-mail: igor.rouzine@gladstone.ucsf.edu

Affiliation The Gladstone Institutes, Gladstone Institute of Virology and Immunology, University of California San Francisco, San Francisco, California, United States of America
⨯
John M. Coffin,

Affiliations Tufts University, Sackler School of Biomedical Sciences, Boston, Massachusetts, United States of America, HIV Drug Resistance Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America
⨯
Leor S. Weinberger

Affiliation The Gladstone Institutes, Gladstone Institute of Virology and Immunology, University of California San Francisco, San Francisco, California, United States of America
⨯

Fifteen Years Later: Hard and Soft Selection Sweeps Confirm a Large Population Number for HIV In Vivo

Igor M. Rouzine,
John M. Coffin,
Leor S. Weinberger

Published: February 20, 2014
https://doi.org/10.1371/journal.pgen.1004179

About the Authors

Igor M. Rouzine

* E-mail: igor.rouzine@gladstone.ucsf.edu

Affiliation The Gladstone Institutes, Gladstone Institute of Virology and Immunology, University of California San Francisco, San Francisco, California, United States of America

John M. Coffin

Affiliations Tufts University, Sackler School of Biomedical Sciences, Boston, Massachusetts, United States of America, HIV Drug Resistance Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America

Leor S. Weinberger

Affiliation The Gladstone Institutes, Gladstone Institute of Virology and Immunology, University of California San Francisco, San Francisco, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

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HIV
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Census
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Population size
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Viral evolution
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Evolutionary genetics
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Evolutionary immunology
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Population genetics
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Antiretroviral therapy
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