About the Authors

Juliette Faraco

Contributed equally to this work with: Juliette Faraco, Ling Lin

Affiliation Center for Sleep Sciences and Medicine, Stanford University, Palo Alto, California, United States of America

Ling Lin

Contributed equally to this work with: Juliette Faraco, Ling Lin

Affiliation Center for Sleep Sciences and Medicine, Stanford University, Palo Alto, California, United States of America

Birgitte Rahbek Kornum

Affiliations Center for Sleep Sciences and Medicine, Stanford University, Palo Alto, California, United States of America, Center for Sleep Medicine, Department of Clinical Neurophysiology, Faculty of Health Sciences, University of Copenhagen, Glostrup Hospital, Copenhagen, Denmark

Eimear E. Kenny

Affiliation Department of Genetics, Stanford University, Palo Alto, California, United States of America

Gosia Trynka

Affiliation University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands

Mali Einen

Affiliation Center for Sleep Sciences and Medicine, Stanford University, Palo Alto, California, United States of America

Tom J. Rico

Affiliation Center for Sleep Sciences and Medicine, Stanford University, Palo Alto, California, United States of America

Peter Lichtner

Affiliation Institute of Human Genetics, Helmholtz Zentrum München–German Research Center for Environmental Health, Munich, Germany

Yves Dauvilliers

Affiliations National Reference Network for Orphan Diseases (Narcolepsy and Idiopathic Hypersomnia), Paris, France, Sleep Unit, Gui-de-Chauliac Hospital, INSERM-1061, Montpellier, France

Isabelle Arnulf

Affiliations National Reference Network for Orphan Diseases (Narcolepsy and Idiopathic Hypersomnia), Paris, France, Sleep Disorders Unit, Hospital Pitié-Salpêtrière, Pierre and Marie Curie University, Paris, France

Michel Lecendreux

Affiliations National Reference Network for Orphan Diseases (Narcolepsy and Idiopathic Hypersomnia), Paris, France, Centre Pédiatrique des Pathologies du Sommeil, Hôpital Robert Debré, Paris, France

Sirous Javidi

Affiliations Hephata-Klinik, Schwalmstadt-Treysa, Germany, Department of Neurology, Philipps University of Marburg, Marburg, Germany

Peter Geisler

Affiliation Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany

Geert Mayer

Affiliations Hephata-Klinik, Schwalmstadt-Treysa, Germany, Department of Neurology, Philipps University of Marburg, Marburg, Germany

Fabio Pizza

Affiliation Department of Neurological Sciences, University of Bologna/IRCCS Istituto delle Scienze Neurologiche, Bologna, Italy

Francesca Poli

Affiliation Department of Neurological Sciences, University of Bologna/IRCCS Istituto delle Scienze Neurologiche, Bologna, Italy

Giuseppe Plazzi

Affiliations Center for Sleep Sciences and Medicine, Stanford University, Palo Alto, California, United States of America, Department of Neurological Sciences, University of Bologna/IRCCS Istituto delle Scienze Neurologiche, Bologna, Italy

Sebastiaan Overeem

Affiliation Kempenhaeghe Centre for Sleep Medicine, Heeze, The Netherlands

Gert Jan Lammers

Affiliation Leiden University Medical Center, Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands

David Kemlink

Affiliation Department of Neurology, Charles University, 1st Faculty of Medicine and General Teaching Hospital, Prague, Czech Republic

Karel Sonka

Affiliation Department of Neurology, Charles University, 1st Faculty of Medicine and General Teaching Hospital, Prague, Czech Republic

Sona Nevsimalova

Affiliation Department of Neurology, Charles University, 1st Faculty of Medicine and General Teaching Hospital, Prague, Czech Republic

Guy Rouleau

Affiliation CHU Ste-Justine Research Centre, Centre of Excellence in Neuromics, Université de Montréal (CENUM), Montreal, Quebec, Canada

Alex Desautels

Affiliations Neurology Service, Hôpital du Sacré-Coeur, Université de Montréal, Montréal, Quebec, Canada, Center for Advanced Research in Sleep Medicine, Hôpital du Sacré-Cœur, Université de Montréal, Montréal, Québec, Canada

Jacques Montplaisir

Affiliation Center for Advanced Research in Sleep Medicine, Hôpital du Sacré-Cœur, Université de Montréal, Montréal, Québec, Canada

Birgit Frauscher

Affiliation Department of Neurology, Innsbruck Medical University, Innsbruck, Austria

Laura Ehrmann

Affiliation Department of Neurology, Innsbruck Medical University, Innsbruck, Austria

Birgit Högl

Affiliation Department of Neurology, Innsbruck Medical University, Innsbruck, Austria

Poul Jennum

Affiliation Center for Sleep Medicine, Department of Clinical Neurophysiology, Faculty of Health Sciences, University of Copenhagen, Glostrup Hospital, Copenhagen, Denmark

Patrice Bourgin

Affiliation University Sleep Clinic and CNRS UPR3212, Strasbourg University Hospital, Strasbourg University, Strasbourg, France

Rosa Peraita-Adrados

Affiliation Sleep and Epilepsy Unit-Clinical Neurophysiology Service, University Hospital Gregorio Marañón, Madrid, Spain

Alex Iranzo

Affiliation Neurology Service and Multisciplinary Sleep Unit, Hospital Clínic, CIBERNED, IDIBAPS, Barcelona, Spain

Claudio Bassetti

Affiliation Department of Neurology, Inselspital Universitatsspital, Bern, Swizerland

Wei-Min Chen

Affiliation Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America

Patrick Concannon

Affiliation Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America

Susan D. Thompson

Affiliation Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America

Vincent Damotte

Affiliations Inserm, U975, CRICM, Paris, France, Pierre Marie Curie University, UMR-S975, Paris, France

Bertrand Fontaine

Affiliations Inserm, U975, CRICM, Paris, France, Pierre Marie Curie University, UMR-S975, Paris, France, Assistance Publique-Hôpitaux de Paris, Department of Neurology, Hospital Pitié-Salpêtrière, Paris, France

Maxime Breban

Affiliations Cochin Institute, INSERM U1016/CNRS UMR 8104/Paris Descartes University, Paris, France, Department of Rheumatology, Ambroise Paré Hospital AP-HP, Boulogne-Billancourt, France, Université Versailles Saint Quentin en Yvelines (UVSQ), Boulogne-Billancourt, France

Christian Gieger

Affiliation Institute of Genetic Epidemiology, Helmholtz Zentrum München, Munich, Germany

Norman Klopp

Affiliation Institute of Genetic Epidemiology, Helmholtz Zentrum München, Munich, Germany

Panos Deloukas

Affiliation Wellcome Trust Sanger Institute, Hinxton, United Kingdom

Cisca Wijmenga

Affiliation University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands

Joachim Hallmayer

Affiliations Center for Sleep Sciences and Medicine, Stanford University, Palo Alto, California, United States of America, Department of Psychiatry, Stanford University School of Medicine, Palo Alto, California, United States of America

Suna Onengut-Gumuscu

Affiliation Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America

Stephen S. Rich

Affiliation Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America

Juliane Winkelmann

Affiliations Institute of Human Genetics, Helmholtz Zentrum München–German Research Center for Environmental Health, Munich, Germany, Institute for Human Genetics, Klinikum rechts der Isar, Technische Universität München, Munich, Germany, Neurology Clinic, Klinikum rechts der Isar, Technische Universität München, Munich, Germany, Munich Cluster for Systems Neurology (SyNergy), Munich, Germany

Emmanuel Mignot

mignot@stanford.edu

Affiliation Center for Sleep Sciences and Medicine, Stanford University, Palo Alto, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: J Faraco, L Lin, P Deloukas, J Hallmayer, SS Rich, E Mignot. Performed the experiments: J Faraco, L Lin, BR Kornum, G Trynka, TJ Rico, P Lichtner, W-M Chen, S Onengut-Gumuscu, SS Rich, J Winkelmann P Concannon. Analyzed the data: J Faraco, L Lin, J Hallmayer, EE Kenny, BR Kornum, E Mignot. Contributed reagents/materials/analysis tools: A Desautels, A Iranzo, B Frauscher, B Fontaine, B Högl, C Bassetti, C Gieger, C Wijmenga, D Kemlink, EE Kenny, E Mignot, F Pizza, F Poli, GJ Lammer, G Mayer, G Plazzi, G Rouleau, G Trynka, I Arnulf, J Montplaisir, J Winkelmann, K Sonka, L Ehrmann, M Breban, M Einen, M Lecendreux, N Klopp, P Bourgin, P Concannon, P Deloukas, P Geisler, P Jennum, P Lichtner, R Peraita-Adrados, S Javidi, S Nevsimalova, S Overeem, S Onengut-Gumuscu, SS Rich, SD Thompson, TJ Rico, V Damotte, W-M Chen, Y Dauvilliers, J Hallmayer. Wrote the paper: J Faraco, J Hallmayer, EE Kenny, SS Rich, P Deloukas, J Winkelmann, E Mignot.