About the Authors

Jing Dong

Contributed equally to this work with: Jing Dong, Guangfu Jin

Affiliations Department of Epidemiology and Biostatistics and Ministry of Education (MOE) Key Lab for Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China, Section of Clinical Epidemiology, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention, and Treatment, Cancer Center, Nanjing Medical University, Nanjing, China, State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China

Guangfu Jin

Contributed equally to this work with: Jing Dong, Guangfu Jin

Affiliations Department of Epidemiology and Biostatistics and Ministry of Education (MOE) Key Lab for Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China, Section of Clinical Epidemiology, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention, and Treatment, Cancer Center, Nanjing Medical University, Nanjing, China

Chen Wu

Affiliation State Key Laboratory of Molecular Oncology and Department of Etiology and Carcinogenesis, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Huan Guo

Affiliation Institute of Occupational Medicine and Ministry of Education Key Laboratory for Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

Baosen Zhou

Affiliation Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China

Jiachun Lv

Affiliation The Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical College, Guangzhou, China

Daru Lu

Affiliation State Key Laboratory of Genetic Engineering, Center for Fudan–VARI Genetic Epidemiology and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China

Yongyong Shi

Affiliation Bio-X Center and Affiliated Changning Mental Health Center, Ministry of Education Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Shanghai JiaoTong University, Shanghai, China

Yongqian Shu

Affiliation Department of Thoracic Surgery and Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China

Lin Xu

Affiliation Department of Thoracic Surgery, Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Nanjing, China

Minjie Chu

Affiliation Department of Epidemiology and Biostatistics and Ministry of Education (MOE) Key Lab for Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China

Cheng Wang

Affiliation Department of Epidemiology and Biostatistics and Ministry of Education (MOE) Key Lab for Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China

Ruyang Zhang

Affiliation Department of Epidemiology and Biostatistics and Ministry of Education (MOE) Key Lab for Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China

Juncheng Dai

Affiliation Department of Epidemiology and Biostatistics and Ministry of Education (MOE) Key Lab for Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China

Yue Jiang

Affiliation Department of Epidemiology and Biostatistics and Ministry of Education (MOE) Key Lab for Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China

Dianke Yu

Affiliation State Key Laboratory of Molecular Oncology and Department of Etiology and Carcinogenesis, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Hongxia Ma

Affiliation Department of Epidemiology and Biostatistics and Ministry of Education (MOE) Key Lab for Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China

Xueying Zhao

Affiliation State Key Laboratory of Genetic Engineering, Center for Fudan–VARI Genetic Epidemiology and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China

Zhihua Yin

Affiliation Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China

Lei Yang

Affiliation The Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical College, Guangzhou, China

Zhiqiang Li

Affiliation Bio-X Center and Affiliated Changning Mental Health Center, Ministry of Education Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Shanghai JiaoTong University, Shanghai, China

Qifei Deng

Affiliation Institute of Occupational Medicine and Ministry of Education Key Laboratory for Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

Songyu Cao

Affiliation Department of Epidemiology and Biostatistics and Ministry of Education (MOE) Key Lab for Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China

Zhenzhen Qin

Affiliation Department of Epidemiology and Biostatistics and Ministry of Education (MOE) Key Lab for Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China

Jianhang Gong

Affiliation Department of Epidemiology and Biostatistics and Ministry of Education (MOE) Key Lab for Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China

Chongqi Sun

Affiliation Department of Epidemiology and Biostatistics and Ministry of Education (MOE) Key Lab for Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China

Jiucun Wang

Affiliation State Key Laboratory of Genetic Engineering, Center for Fudan–VARI Genetic Epidemiology and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China

Wei Wu

Affiliation Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China

Guoquan Zhou

Affiliation Bio-X Center and Affiliated Changning Mental Health Center, Ministry of Education Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Shanghai JiaoTong University, Shanghai, China

Hongyan Chen

Affiliation State Key Laboratory of Genetic Engineering, Center for Fudan–VARI Genetic Epidemiology and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China

Peng Guan

Affiliation Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China

Yijiang Chen

Affiliation Department of Thoracic Surgery and Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China

Xiangyang Liu

Affiliation Department of Thoracic Surgery, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Li Liu

Affiliation Cancer Center of Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

Pin Xu

Affiliation Department of Oncology, Wuhan Iron and Steel Group/Corporation Staff-Worker Hospital, Wuhan, China

Baohui Han

Affiliation Department of Respiratory Disease, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China

Chunxue Bai

Affiliation Department of Respiratory Disease, Zhongshan Hospital, Fudan University, Shanghai, China

Yuxia Zhao

Affiliation Department of Radiation Oncology, First Affiliated Hospital of China Medical University, Shenyang, China

Haibo Zhang

Affiliation Department of Radiotherapy, Shenyang Northern Hospital, Shenyang, China

Ying Yan

Affiliation Department of Radiotherapy, Shenyang Northern Hospital, Shenyang, China

Jibin Liu

Affiliation Department of Surgery, Nantong Cancer Hospital, Nantong, China

Christopher I. Amos

Affiliation Department of Genetics, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

Feng Chen

Affiliation Department of Epidemiology and Biostatistics and Ministry of Education (MOE) Key Lab for Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China

Wen Tan

Affiliation State Key Laboratory of Molecular Oncology and Department of Etiology and Carcinogenesis, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Li Jin

Affiliation State Key Laboratory of Genetic Engineering, Center for Fudan–VARI Genetic Epidemiology and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China

Tangchun Wu

Affiliation Institute of Occupational Medicine and Ministry of Education Key Laboratory for Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

Zhibin Hu

zhibin_hu@njmu.edu.cn (Z Hu); ldongxin@gmail.com (D Lin); hbshen@njmu.edu.cn (H Shen)

Affiliations Department of Epidemiology and Biostatistics and Ministry of Education (MOE) Key Lab for Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China, Section of Clinical Epidemiology, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention, and Treatment, Cancer Center, Nanjing Medical University, Nanjing, China, State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China

Dongxin Lin

zhibin_hu@njmu.edu.cn (Z Hu); ldongxin@gmail.com (D Lin); hbshen@njmu.edu.cn (H Shen)

Affiliation State Key Laboratory of Molecular Oncology and Department of Etiology and Carcinogenesis, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Hongbing Shen

zhibin_hu@njmu.edu.cn (Z Hu); ldongxin@gmail.com (D Lin); hbshen@njmu.edu.cn (H Shen)

Affiliations Department of Epidemiology and Biostatistics and Ministry of Education (MOE) Key Lab for Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China, Section of Clinical Epidemiology, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention, and Treatment, Cancer Center, Nanjing Medical University, Nanjing, China, State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: H Shen, Z Hu, J Dong, G Jin, D Lin. Performed the experiments: M Chu, C Wang, Y Jiang, S Cao, Z Qin, J Gong, C Sun. Analyzed the data: J Dong, G Jin, J Dai, R Zhang, Z Li. Contributed reagents/materials/analysis tools: Y Shu, L Xu, H Ma, Y Chen, C Wu, D Yu, X Liu, W Tan, H Guo, Q Deng, L Liu, P Xu, X Zhao, J Wang, G Zhou, H Chen, B Han, C Bai, Z Yin, W Wu, P Guan, Y Zhao, H Zhang, Y Yan, L Yang, J Liu, T Wu, Y Shi, D Lu, L Jin, B Zhou, J Lv. Wrote the paper: J Dong, G Jin. Critical revision of the manuscript for important intellectual content: H Shen, T Wu, Y Shi, D Lu, L Jin, B Zhou, J Lv, CI Amos. Obtained funding: H Shen, Z Hu, D Lin. Administrative, technical, or material support: CI Amos, F Chen. Study supervision: H Shen, D Lin, Z Hu.