About the Authors

Carsten A. Böger

Affiliation Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany

Mathias Gorski

Affiliations Department of Epidemiology and Preventive Medicine, University Hospital Regensburg, Regensburg, Germany, Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Man Li

Affiliation Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

Michael M. Hoffmann

Affiliation Clinical Chemistry, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany

Chunmei Huang

Affiliation Division of Nephrology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Qiong Yang

Affiliation Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America

Alexander Teumer

Affiliation Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany

Vera Krane

Affiliation University of Würzburg, Department of Medicine 1, Division of Nephrology, University Hospital Würzburg, Würzburg, Germany

Conall M. O'Seaghdha

Affiliations Division of Nephrology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, NHLBI's Framingham Heart Study and the Center for Population Studies, Framingham, Massachusetts, United States of America

Zoltán Kutalik

Affiliations Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland, Swiss Institute of Bioinformatics, Lausanne, Switzerland

H.-Erich Wichmann

Affiliations Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Institute of Medical Informatics, Biometry, and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany, Klinikum Großhadern, Munich, Germany

Thomas Haak

Affiliation Diabetes Klinik Bad Mergentheim, Bad Mergentheim, Germany

Eva Boes

Affiliation Innsbruck Medical University, Division of Genetic Epidemiology, Innsbruck, Austria

Stefan Coassin

Affiliation Innsbruck Medical University, Division of Genetic Epidemiology, Innsbruck, Austria

Josef Coresh

Affiliation Department of Epidemiology and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

Barbara Kollerits

Affiliation Innsbruck Medical University, Division of Genetic Epidemiology, Innsbruck, Austria

Margot Haun

Affiliation Innsbruck Medical University, Division of Genetic Epidemiology, Innsbruck, Austria

Bernhard Paulweber

Affiliation First Department of Internal Medicine, Paracelsus Medical University, Salzburg, Austria

Anna Köttgen

Affiliations Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America, Renal Division, University Hospital of Freiburg, Freiburg, Germany

Guo Li

Affiliation Department of Medicine, University of Washington, Seattle, Washington, United States of America

Michael G. Shlipak

Affiliations Division of General Internal Medicine, San Francisco VA Medical Center, San Francisco, California, United States of America, Department of Medicine, Epidemiology, and Biostatistics, University of California San Francisco, San Francisco, California, United States of America

Neil Powe

Affiliation Department of Medicine, San Francisco General Hospital and University of California San Francisco, San Francisco, California, United States of America

Shih-Jen Hwang

Affiliation NHLBI's Framingham Heart Study and the Center for Population Studies, Framingham, Massachusetts, United States of America

Abbas Dehghan

Affiliations Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands, Member of Netherlands Consortium for Healthy Aging (NCHA), Netherlands Genomics Initiative (NGI), Leiden, The Netherlands

Fernando Rivadeneira

Affiliations Member of Netherlands Consortium for Healthy Aging (NCHA), Netherlands Genomics Initiative (NGI), Leiden, The Netherlands, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

André Uitterlinden

Affiliations Member of Netherlands Consortium for Healthy Aging (NCHA), Netherlands Genomics Initiative (NGI), Leiden, The Netherlands, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands

Albert Hofman

Affiliations Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands, Member of Netherlands Consortium for Healthy Aging (NCHA), Netherlands Genomics Initiative (NGI), Leiden, The Netherlands

Jacques S. Beckmann

Affiliation Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois and Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland

Bernhard K. Krämer

Affiliation University Medical Centre Mannheim, 5th Department of Medicine, Mannheim, Germany

Jacqueline Witteman

Affiliations Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands, Member of Netherlands Consortium for Healthy Aging (NCHA), Netherlands Genomics Initiative (NGI), Leiden, The Netherlands

Murielle Bochud

Affiliation University Institute of Social and Preventive Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland

David Siscovick

Affiliation Cardiovascular Health Research Unit, Departments of Epidemiology and Medicine, University of Washington, Seattle, Washington, United States of America

Rainer Rettig

Affiliation Institute of Physiology, University of Greifswald, Greifswald, Germany

Florian Kronenberg

Affiliation Innsbruck Medical University, Division of Genetic Epidemiology, Innsbruck, Austria

Christoph Wanner

Affiliation University of Würzburg, Department of Medicine 1, Division of Nephrology, University Hospital Würzburg, Würzburg, Germany

Ravi I. Thadhani

Affiliation Division of Nephrology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Iris M. Heid

Affiliations Department of Epidemiology and Preventive Medicine, University Hospital Regensburg, Regensburg, Germany, Institute of Epidemiology I, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Caroline S. Fox

Contributed equally to this work with: Caroline S. Fox, W. H. Kao

foxca@nhlbi.nih.gov (CSF); wkao@jhsph.edu (WHK)

Affiliations NHLBI's Framingham Heart Study and the Center for Population Studies, Framingham, Massachusetts, United States of America, Division of Endocrinology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

W. H. Kao

Contributed equally to this work with: Caroline S. Fox, W. H. Kao

foxca@nhlbi.nih.gov (CSF); wkao@jhsph.edu (WHK)

Affiliation Department of Epidemiology and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

The CKDGen Consortium

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CAB MG MMH CH AT VK H-EW JC EB BP AK MGS NP JW AD JSB BKK MB DS RR FK CW RIT IMH CSF WHK. Wrote the paper: CAB MG ML MMH CH QY AD DS FK CSF WHK IMH MB RR RIT. Study management: CAB MMH CH VK H-EW TH JC BK BP MH AK GL MGS NP JW JSB BKK AD MB DS RR FK CW RIT IMH CSF WHK. Subject recruitment: CAB CH VK H-EW TH JC BK BP SC EB MGS NP JW BKK MB DS RR FK CW RIT CSF WHK. Interpretation of results: CAB MG ML MMH CH AT CMO ZK AK GL EB SC BP BK MGS AD MB DS CW VK RR FK IMH CSF WHK. Critical review of manuscript: CAB MG ML MMH CH QY AT VK CMO ZK H-EW TH EB SC JC BK MH BP AK GL MGS NP S-JH CMO JW AH AU FR JSB BKK AD MB DS RR FK CW RIT IMH CSF WHK. Statistical methods and analysis: CAB MG ML MMH CH QY AT CMO ZK BK GL AD MB DS FK IMH CSF WHK. Genotyping: CAB MMH H-EW SC FK MH MGS DS JW AD JSB MB RIT IMH CSF WHK. Bio-informatics: CAB MG ML MMH AT CMO QY ZK SC AK GL AD MB DS IMH CSF WHK.