Local Absence of Secondary Structure Permits Translation of mRNAs that Lack Ribosome-Binding Sites

Lars B. Scharff; Liam Childs; Dirk Walther; Ralph Bock

doi:10.1371/journal.pgen.1002155

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Peer-reviewed

Research Article

Local Absence of Secondary Structure Permits Translation of mRNAs that Lack Ribosome-Binding Sites

Lars B. Scharff ,

Contributed equally to this work with: Lars B. Scharff, Liam Childs

Affiliation Max-Planck-Institut für Molekulare Pflanzenphysiologie, Potsdam-Golm, Germany
⨯
Liam Childs ,

Contributed equally to this work with: Lars B. Scharff, Liam Childs

Affiliation Max-Planck-Institut für Molekulare Pflanzenphysiologie, Potsdam-Golm, Germany
⨯
Dirk Walther,

Affiliation Max-Planck-Institut für Molekulare Pflanzenphysiologie, Potsdam-Golm, Germany
⨯
Ralph Bock

* E-mail: rbock@mpimp-golm.mpg.de

Affiliation Max-Planck-Institut für Molekulare Pflanzenphysiologie, Potsdam-Golm, Germany
⨯

Local Absence of Secondary Structure Permits Translation of mRNAs that Lack Ribosome-Binding Sites

Lars B. Scharff,
Liam Childs,
Dirk Walther,
Ralph Bock

Published: June 23, 2011
https://doi.org/10.1371/journal.pgen.1002155

About the Authors

Lars B. Scharff

Contributed equally to this work with: Lars B. Scharff, Liam Childs

Affiliation Max-Planck-Institut für Molekulare Pflanzenphysiologie, Potsdam-Golm, Germany

Liam Childs

Contributed equally to this work with: Lars B. Scharff, Liam Childs

Affiliation Max-Planck-Institut für Molekulare Pflanzenphysiologie, Potsdam-Golm, Germany

Dirk Walther

Affiliation Max-Planck-Institut für Molekulare Pflanzenphysiologie, Potsdam-Golm, Germany

Ralph Bock

* E-mail: rbock@mpimp-golm.mpg.de

Affiliation Max-Planck-Institut für Molekulare Pflanzenphysiologie, Potsdam-Golm, Germany

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LBS LC DW RB. Performed the experiments: LBS LC. Analyzed the data: LBS LC DW RB. Wrote the paper: RB. Provided significant input on manuscript: LBS LC DW.

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Sequence motif analysis
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Messenger RNA
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RNA structure
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Untranslated regions
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Translation initiation
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Plastids
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Protein translation
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Nucleotides
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