About the Authors

Deniz Simsek

Contributed equally to this work with: Deniz Simsek, Erika Brunet

Affiliations Developmental Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America, Weill Cornell Graduate School of Medical Sciences, New York, New York, United States of America

Erika Brunet

Contributed equally to this work with: Deniz Simsek, Erika Brunet

Affiliations Museum National d'Histoire Naturelle, Paris, France, CNRS, UMR7196, Paris, France, Inserm, U565, Paris, France

Sunnie Yan-Wai Wong

Affiliation Sangamo BioSciences, Richmond, California, United States of America

Sachin Katyal

Affiliation Department of Genetics and Tumor Cell Biology, St Jude Children's Research Hospital, Memphis, Tennessee, United States of America

Yankun Gao

Affiliation Department of Genetics and Tumor Cell Biology, St Jude Children's Research Hospital, Memphis, Tennessee, United States of America

Peter J. McKinnon

Affiliation Department of Genetics and Tumor Cell Biology, St Jude Children's Research Hospital, Memphis, Tennessee, United States of America

Jacqueline Lou

Affiliation Sangamo BioSciences, Richmond, California, United States of America

Lei Zhang

Affiliation Sangamo BioSciences, Richmond, California, United States of America

James Li

Affiliation Sangamo BioSciences, Richmond, California, United States of America

Edward J. Rebar

Affiliation Sangamo BioSciences, Richmond, California, United States of America

Philip D. Gregory

Affiliation Sangamo BioSciences, Richmond, California, United States of America

Michael C. Holmes

Affiliation Sangamo BioSciences, Richmond, California, United States of America

Maria Jasin

m-jasin@ski.mskcc.org

Affiliations Developmental Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America, Weill Cornell Graduate School of Medical Sciences, New York, New York, United States of America

Competing Interests

SY-W Wong, J Lou, L Zhang, J Li, EJ Rebar, PD Gregory, and MC Holmes are full-time employees of Sangamo BioSciences.

Author Contributions

Conceived and designed the experiments: D Simsek, E Brunet, M Jasin. Performed the experiments: D Simsek, E Brunet, SY-W Wong. Analyzed the data: D Simsek, E Brunet, SY-W Wong, M Jasin. Contributed reagents/materials/analysis tools: S Katyal, Y Gao, PJ McKinnon, J Lou, L Zhang, SY-W Wong, J Li, EJ Rebar, PD Gregory, MC Holmes. Wrote the paper: D Simsek, E Brunet, M Jasin.