About the Authors

Ya-Chu Chang

Contributed equally to this work with: Ya-Chu Chang, Wan-Tzu Hung

Affiliation Institute of Biotechnology, Department of Life Science, National Tsing Hua University, Hsinchu, Taiwan

Wan-Tzu Hung

Contributed equally to this work with: Ya-Chu Chang, Wan-Tzu Hung

Affiliation Institute of Biotechnology, Department of Life Science, National Tsing Hua University, Hsinchu, Taiwan

Yun-Chin Chang

Affiliation Institute of Biotechnology, Department of Life Science, National Tsing Hua University, Hsinchu, Taiwan

Henry C. Chang

Affiliation Department of Biological Sciences, Purdue University, West Lafayette, Indiana, United States of America

Chia-Lin Wu

Affiliations Institute of Biotechnology, Department of Life Science, National Tsing Hua University, Hsinchu, Taiwan, Brain Research Center, National Tsing Hua University, Hsinchu, Taiwan

Ann-Shyn Chiang

Affiliations Institute of Biotechnology, Department of Life Science, National Tsing Hua University, Hsinchu, Taiwan, Brain Research Center, National Tsing Hua University, Hsinchu, Taiwan

George R. Jackson

Affiliations Department of Neurology, Neuroscience, and Cell Biology, University of Texas Medical Branch, Galveston, Texas, United States of America, Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, United States of America, Mitchell Center for Neurodegenerative Diseases, University of Texas Medical Branch, Galveston, Texas, United States of America

Tzu-Kang Sang

tksang@life.nthu.edu.tw

Affiliations Institute of Biotechnology, Department of Life Science, National Tsing Hua University, Hsinchu, Taiwan, Brain Research Center, National Tsing Hua University, Hsinchu, Taiwan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: Ya-Chu Chang, Wan-Tzu Hung, Henry C Chang, Tzu-Kang Sang. Performed the experiments: Ya-Chu Chang, Wan-Tzu Hung, Yun-Chin Chang, Chia-Lin Wu, Tzu-Kang Sang. Analyzed the data: Ya-Chu Chang, Wan-Tzu Hung, Yun-Chin Chang, Chia-Lin Wu, Tzu-Kang Sang. Contributed reagents/materials/analysis tools: Henry C Chang, Ann-Shyn Chiang, George R Jackson. Wrote the paper: Ya-Chu Chang, Henry C Chang, Tzu-Kang Sang.