About the Authors

Yen Ling Low

Contributed equally to this work with: Yen Ling Low, Yuqing Li, Keith Humphreys

Affiliation Human Genetics, Genome Institute of Singapore, Singapore, Singapore

Yuqing Li

Contributed equally to this work with: Yen Ling Low, Yuqing Li, Keith Humphreys

Affiliation Human Genetics, Genome Institute of Singapore, Singapore, Singapore

Keith Humphreys

Contributed equally to this work with: Yen Ling Low, Yuqing Li, Keith Humphreys

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Anbupalam Thalamuthu

Affiliation Human Genetics, Genome Institute of Singapore, Singapore, Singapore

Yi Li

Affiliation Human Genetics, Genome Institute of Singapore, Singapore, Singapore

Hatef Darabi

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Sara Wedrén

Affiliation Institute for Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

Carine Bonnard

Affiliation Human Genetics, Genome Institute of Singapore, Singapore, Singapore

Kamila Czene

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Mark M. Iles

Affiliation Section of Epidemiology and Biostatistics, Leeds Institute of Molecular Medicine, St. James's University Hospital, Leeds, United Kingdom

Tuomas Heikkinen

Affiliation Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland

Kristiina Aittomäki

Affiliation Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland

Carl Blomqvist

Affiliations Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland, Department of Oncology, Radiology, and Clinical Immunology, Uppsala University Hospital, Uppsala, Sweden

Heli Nevanlinna

Affiliation Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland

Per Hall

liuj3@gis.a-star.edu.sg (JL); liue@gis.a-star.edu.sg (ETL); Per.Hall@ki.se (PH)

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Edison T. Liu

liuj3@gis.a-star.edu.sg (JL); liue@gis.a-star.edu.sg (ETL); Per.Hall@ki.se (PH)

Affiliation Cancer Biology, Genome Institute of Singapore, Singapore, Singapore

Jianjun Liu

liuj3@gis.a-star.edu.sg (JL); liue@gis.a-star.edu.sg (ETL); Per.Hall@ki.se (PH)

Affiliation Human Genetics, Genome Institute of Singapore, Singapore, Singapore

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: Keith Humphreys, Sara Wedrén, Heli Nevanlinna, Per Hall, Edison T. Liu, Jianjun Liu. Performed the experiments: Yuqing Li, Carine Bonnard. Analyzed the data: Yuqing Li, Keith Humphreys, Anbupalam Thalamuthu, Yi Li, Hatef Darabi, Mark M. Iles. Contributed reagents/materials/analysis tools: Sara Wedrén, Tuomas Heikkinen, Kristiina Aittomäki, Carl Blomqvist. Wrote the paper: Yen Ling Low, Keith Humphreys, Kamila Czene, Per Hall, Edison T. Liu, Jianjun Liu.