About the Authors

André Scherag

andre.scherag@uk-essen.de (AS); p.froguel@imperial.ac.uk (PF)

Affiliations Institute for Medical Informatics, Biometry and Epidemiology, University of Duisburg-Essen, Essen, Germany, Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen, Germany

Christian Dina

Affiliation Centre National de la Recherche Scientifique (CNRS) 8090-Institute of Biology, Pasteur Institute, Lille, France

Anke Hinney

Affiliation Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen, Germany

Vincent Vatin

Affiliation Centre National de la Recherche Scientifique (CNRS) 8090-Institute of Biology, Pasteur Institute, Lille, France

Susann Scherag

Affiliation Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen, Germany

Carla I. G. Vogel

Affiliation Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen, Germany

Timo D. Müller

Affiliations Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen, Germany, Department of Psychiatry, University of Cincinnati Genome Research Institute, Cincinnati, Ohio, United States of America

Harald Grallert

Affiliation Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Epidemiology, Munich-Neuherberg, Germany

H.-Erich Wichmann

Affiliations Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Epidemiology, Munich-Neuherberg, Germany, Institute of Medical Data Management, Biometrics, and Epidemiology, Ludwig-Maximilians University Munich, Munich, Germany

Beverley Balkau

Affiliation INSERM, CESP Centre for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease over the Lifecourse, Université Paris Sud 11, UMRS 1018, Villejuif, France

Barbara Heude

Affiliation INSERM, CESP Centre for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease over the Lifecourse, Université Paris Sud 11, UMRS 1018, Villejuif, France

Marjo-Riitta Jarvelin

Affiliations Department of Epidemiology and Public Health, Imperial College London, London, United Kingdom, Institute of Health Sciences, Department of Child and Adolescent Health, National Public Health Institute, Biocenter Oulu, University of Oulu, Oulu, Finland

Anna-Liisa Hartikainen

Affiliation Department of Clinical Sciences/Obstetrics and Gynecology, University of Oulu, Oulu, Finland

Claire Levy-Marchal

Affiliation INSERM, U690, Université Paris Diderot, Paris, France

Jacques Weill

Affiliation Pediatric Endocrine Unit, Jeanne de Flandre Hospital, Lille, France

Jérôme Delplanque

Affiliation Centre National de la Recherche Scientifique (CNRS) 8090-Institute of Biology, Pasteur Institute, Lille, France

Antje Körner

Affiliation University Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany

Wieland Kiess

Affiliation University Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany

Peter Kovacs

Affiliation Department of Internal Medicine III, Interdisciplinary Centre for Clinical Research, University of Leipzig, Leipzig, Germany

Nigel W. Rayner

Affiliations Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Inga Prokopenko

Affiliations Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Mark I. McCarthy

Affiliations Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Helmut Schäfer

Affiliation Institute of Medical Biometry and Epidemiology, Philipps-University of Marburg, Marburg, Germany

Ivonne Jarick

Affiliation Institute of Medical Biometry and Epidemiology, Philipps-University of Marburg, Marburg, Germany

Heiner Boeing

Affiliation Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany

Eva Fisher

Affiliation Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany

Thomas Reinehr

Affiliation Institute for Paediatric Nutrition Medicine, Vestische Hospital for Children and Adolescents, University of Witten/Herdecke, Datteln, Germany

Joachim Heinrich

Affiliations Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Epidemiology, Munich-Neuherberg, Germany, Institute of Medical Data Management, Biometrics, and Epidemiology, Ludwig-Maximilians University Munich, Munich, Germany

Peter Rzehak

Affiliations Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Epidemiology, Munich-Neuherberg, Germany, Institute of Medical Data Management, Biometrics, and Epidemiology, Ludwig-Maximilians University Munich, Munich, Germany

Dietrich Berdel

Affiliation Department of Paediatrics, Marien-Hospital Wesel, Wesel, Germany

Michael Borte

Affiliations Children's Hospital, Municipal Hospital “St Georg”, Leipzig, Germany, Department of Pediatrics, University of Leipzig, Leipzig, Germany

Heike Biebermann

Affiliation Institute of Experimental Pediatric Endocrinology, Charité-Universitätsmedizin Berlin, Berlin, Germany

Heiko Krude

Affiliation Institute of Experimental Pediatric Endocrinology, Charité-Universitätsmedizin Berlin, Berlin, Germany

Dieter Rosskopf

Affiliation Institute for Pharmacology, Ernst-Moritz-Arndt University, Greifswald, Germany

Christian Rimmbach

Affiliation Institute for Pharmacology, Ernst-Moritz-Arndt University, Greifswald, Germany

Winfried Rief

Affiliation Department of Clinical Psychology and Psychotherapy, Faculty of Psychology, University of Marburg, Germany

Tobias Fromme

Affiliation Molecular Nutritional Medicine, Technische Universität München, Else Kröner-Fresenius Center, Freising-Weihenstephan, Germany

Martin Klingenspor

Affiliation Molecular Nutritional Medicine, Technische Universität München, Else Kröner-Fresenius Center, Freising-Weihenstephan, Germany

Annette Schürmann

Affiliation Department of Pharmacology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany

Nadja Schulz

Affiliation Department of Pharmacology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany

Markus M. Nöthen

Affiliations Institute of Human Genetics, University of Bonn, Bonn, Germany, Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany

Thomas W. Mühleisen

Affiliations Institute of Human Genetics, University of Bonn, Bonn, Germany, Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany

Raimund Erbel

Affiliation Department of Cardiology, University of Duisburg-Essen, Essen, Germany

Karl-Heinz Jöckel

Affiliation Institute for Medical Informatics, Biometry and Epidemiology, University of Duisburg-Essen, Essen, Germany

Susanne Moebus

Affiliation Institute for Medical Informatics, Biometry and Epidemiology, University of Duisburg-Essen, Essen, Germany

Tanja Boes

Affiliation Institute for Medical Informatics, Biometry and Epidemiology, University of Duisburg-Essen, Essen, Germany

Thomas Illig

Affiliations Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Epidemiology, Munich-Neuherberg, Germany, Institute of Medical Data Management, Biometrics, and Epidemiology, Ludwig-Maximilians University Munich, Munich, Germany

Philippe Froguel

andre.scherag@uk-essen.de (AS); p.froguel@imperial.ac.uk (PF)

Affiliations Centre National de la Recherche Scientifique (CNRS) 8090-Institute of Biology, Pasteur Institute, Lille, France, Department of Genomic Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom

Johannes Hebebrand

Affiliation Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen, Germany

David Meyre

Affiliation Centre National de la Recherche Scientifique (CNRS) 8090-Institute of Biology, Pasteur Institute, Lille, France

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Writing team: A. Scherag, A. Hinney, J. Hebebrand, C. Dina, D. Meyre, P. Froguel; all others reviewed and approved the manuscript. Project management: A. Scherag, A. Hinney, J. Hebebrand, C. Dina, D. Meyre, P. Froguel. Genome-wide association sampling, genotyping and imputations: A. Scherag, A. Hinney, J. Hebebrand, C. Dina, V. Vatin, D. Meyre, P. Froguel, S. Scherag, C. I. G. Vogel, T. D. Müller, I. Prokopenko, M. I. McCarthy. Confirmation study sampling, genotyping and follow-up analyses: A. Scherag, C. Dina, A. Hinney, V. Vatin, S. Scherag, C. I. G. Vogel, T.D. Müller, H. Grallert, H.-E. Wichmann, B. Balkau, B. Heude, M.-R. Jarvelin, A.-L. Hartikainen, C. Levy-Marchal, J. Weill, J. Delplanque, A. Körner, W. Kiess, P. Kovacs, H. Boeing, T. Reinehr, J. Heinrich, P. Rzehak, D. Berdel, M. Borte, H. Biebermann, H. Krude, D. Rosskopf, C. Rimmbach, W. Rief, T. Fromme, M. Klingenspor, A. Schürmann, N. Schulz, M. M. Nöthen, T. W. Mühleisen, R. Erbel, K.-H. Jöckel, S. Moebus, T. Illig. Statistical analysis and informatics: A. Scherag, C. Dina, N. W. Rayner, H. Schäfer, I. Jarick, E. Fisher, T. Boes. Candidate gene analysis: A. Scherag.