About the Authors
- Andrew A. Hicks
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Contributed equally to this work with: Andrew A. Hicks, Åsa Johansson, Veronique Vitart, Peter Ugocsai, Yurii Aulchenko
Affiliation Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany
- Peter P. Pramstaller
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* E-mail: peter.pramstaller@eurac.edu (PPP); harry.campbell@ed.ac.uk (HC)
Affiliations Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany, Department of Neurology, General Central Hospital, Bolzano, Italy, Department of Neurology, University of Lübeck, Lübeck, Germany
- Åsa Johansson
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Contributed equally to this work with: Andrew A. Hicks, Åsa Johansson, Veronique Vitart, Peter Ugocsai, Yurii Aulchenko
Affiliation Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
- Veronique Vitart
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Contributed equally to this work with: Andrew A. Hicks, Åsa Johansson, Veronique Vitart, Peter Ugocsai, Yurii Aulchenko
Affiliation MRC Human Genetics Unit, IGMM, Western General Hospital, Edinburgh, United Kingdom
- Igor Rudan
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Affiliations Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom, Croatian Centre for Global Health, Faculty of Medicine, University of Split, Split, Croatia, Gen-info Ltd, Zagreb, Croatia
- Peter Ugocsai
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Contributed equally to this work with: Andrew A. Hicks, Åsa Johansson, Veronique Vitart, Peter Ugocsai, Yurii Aulchenko
Affiliation Institute for Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany
- Yurii Aulchenko
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Contributed equally to this work with: Andrew A. Hicks, Åsa Johansson, Veronique Vitart, Peter Ugocsai, Yurii Aulchenko
Affiliation Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands
- Christopher S. Franklin
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Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
- Gerhard Liebisch
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Affiliation Institute for Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany
- Jeanette Erdmann
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Affiliation Medizinische Klinik II, University of Lübeck, Lübeck, Germany
- Inger Jonasson
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Affiliation Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
- Irina V. Zorkoltseva
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Affiliation Institute of Cytology and Genetics SD RAS, Novosibirsk, Russia
- Cristian Pattaro
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Affiliation Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany
- Caroline Hayward
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Affiliation MRC Human Genetics Unit, IGMM, Western General Hospital, Edinburgh, United Kingdom
- Aaron Isaacs
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Affiliation Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands
- Christian Hengstenberg
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Affiliation Klinik und Poliklinik für Innere Medizin II, Universität Regensburg, Regensburg, Germany
- Susan Campbell
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Affiliation MRC Human Genetics Unit, IGMM, Western General Hospital, Edinburgh, United Kingdom
- Carsten Gnewuch
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Affiliation Institute for Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany
- A. CecileJ.W. Janssens
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Affiliation Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands
- Anatoly V. Kirichenko
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Affiliation Institute of Cytology and Genetics SD RAS, Novosibirsk, Russia
- Inke R. König
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Affiliation Institut für Medizinische Biometrie und Statistik, University of Lübeck, Lübeck, Germany
- Fabio Marroni
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Affiliation Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany
- Ozren Polasek
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Affiliations Gen-info Ltd, Zagreb, Croatia, Andrija Stampar School of Public Health, Faculty of Medicine, University of Zagreb, Zagreb, Croatia
- Ayse Demirkan
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Affiliation Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands
- Ivana Kolcic
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Affiliation Andrija Stampar School of Public Health, Faculty of Medicine, University of Zagreb, Zagreb, Croatia
- Christine Schwienbacher
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Affiliations Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany, Department of Experimental and Diagnostic Medicine, University of Ferrara, Ferrara, Italy
- Wilmar Igl
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Affiliation Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
- Zrinka Biloglav
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Affiliation Andrija Stampar School of Public Health, Faculty of Medicine, University of Zagreb, Zagreb, Croatia
- Jacqueline C. M. Witteman
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Affiliation Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands
- Irene Pichler
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Affiliation Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany
- Ghazal Zaboli
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Affiliation Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
- Tatiana I. Axenovich
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Affiliation Institute of Cytology and Genetics SD RAS, Novosibirsk, Russia
- Annette Peters
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Affiliation Institute of Epidemiology, Helmholtz Zentrum München – German Research Center for Environmental Health, Neuherberg, Germany
- Stefan Schreiber
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Affiliation Institut für Klinische Molekularbiologie, Christian-Albrechts Universität, Kiel, Germany
- H.-Erich Wichmann
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Affiliations Institute of Epidemiology, Helmholtz Zentrum München – German Research Center for Environmental Health, Neuherberg, Germany, Institute of Medical Information Science, Biometry and Epidemiology, Chair of Epidemiology, LMU Munich, Germany
- Heribert Schunkert
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Affiliation Medizinische Klinik II, University of Lübeck, Lübeck, Germany
- Nick Hastie
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Affiliation MRC Human Genetics Unit, IGMM, Western General Hospital, Edinburgh, United Kingdom
- Ben A. Oostra
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Affiliation Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands
- Sarah H. Wild
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Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
- Thomas Meitinger
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¶These authors are joint senior authors on this work.
Affiliation Helmholtz Zentrum München, Neuherberg, Munich, Germany
- Ulf Gyllensten
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¶These authors are joint senior authors on this work.
Affiliation Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
- Cornelia M. van Duijn
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¶These authors are joint senior authors on this work.
Affiliation Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands
- James F. Wilson
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¶These authors are joint senior authors on this work.
Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
- Alan Wright
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¶These authors are joint senior authors on this work.
Affiliation MRC Human Genetics Unit, IGMM, Western General Hospital, Edinburgh, United Kingdom
- Gerd Schmitz
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¶These authors are joint senior authors on this work.
Affiliation Institute for Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany
- Harry Campbell
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* E-mail: peter.pramstaller@eurac.edu (PPP); harry.campbell@ed.ac.uk (HC)
Affiliation Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: P.P. Pramstaller, I. Rudan, J.C.M. Witteman, N. Hastie, B.A. Oostra, T. Meitinger, U. Gyllensten, C.M. van Duijn, J.F. Wilson, A.F. Wright, G. Schmitz, H. Campbell. Performed the experiments: I. Rudan, P. Ugocsai, G. Liebisch, I. Jonasson, C. Hayward, S. Campbell, C. Gnewuch, O. Polasek, I. Kolcic, C. Schwienbacher, Z. Biloglav, I. Pichler, S.H. Wild, T. Meitinger, U. Gyllensten, J.F. Wilson, H. Campbell. Analyzed the data: A.A. Hicks, Å. Johansson, V. Vitart, Y.S. Aulchenko, C.S. Franklin, G. Liebisch, I.V. Zorkolsteva, C. Pattaro, C. Hayward, A. Issacs, A.C.J.W. Janssens, A.V. Kirichenko, F. Marroni, A. Demirkan, W. Igl, G. Zaboli, C.M. van Duijn. Contributed reagents/materials/analysis tools: P.P. Pramstaller, I. Rudan, Y.S. Aulchenko, G. Liebisch, O. Polasek, I. Kolcic, Z. Biloglav, J.C.M. Witteman, T. Axenovich, N. Hastie, B.A. Oostra, T. Meitinger, U. Gyllensten, C.M. van Duijn, J.F. Wilson, A.F. Wright, G. Schmitz, H. Campbell. Wrote the paper: A.A. Hicks, P.P. Pramstaller, Å. Johansson, V. Vitart, I. Rudan, P. Ugocsai, C.M. van Duijn, J.F. Wilson, G. Schmitz, H. Campbell. Responsible for generating the MI association data: J. Erdmann, C. Hengstenberg, I. König, A. Peters, S. Schreiber, H.-E. Wichmann, H. Schunkert.