About the Authors

Christian Gieger

Affiliations Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Institute of Medical Informatics, Biometry, and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany

Ludwig Geistlinger

Affiliation Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Elisabeth Altmaier

Affiliations Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Faculty of Biology, Ludwig-Maximilians-Universität, Planegg-Martinsried, Germany

Martin Hrabé de Angelis

Affiliations Institute of Experimental Genetics, Genome Analysis Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Institute of Experimental Genetics, Life and Food Science Center Weihenstephan, Technische Universität München, Freising-Weihenstephan, Germany

Florian Kronenberg

Affiliation Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria

Thomas Meitinger

Affiliations Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Institute of Human Genetics, Klinikum rechts der Isar, Technische Universität München, Munich, Germany

Hans-Werner Mewes

Affiliations Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Department of Genome-Oriented Bioinformatics, Life and Food Science Center Weihenstephan, Technische Universität München, Freising-Weihenstephan, Germany

H.-Erich Wichmann

Affiliations Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Institute of Medical Informatics, Biometry, and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany

Klaus M. Weinberger

Affiliation Biocrates Life Sciences AG, Innsbruck, Austria

Jerzy Adamski

Affiliations Institute of Experimental Genetics, Genome Analysis Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Institute of Experimental Genetics, Life and Food Science Center Weihenstephan, Technische Universität München, Freising-Weihenstephan, Germany

Thomas Illig

Affiliation Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

Karsten Suhre

karsten.suhre@helmholtz-muenchen.de

Affiliations Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Faculty of Biology, Ludwig-Maximilians-Universität, Planegg-Martinsried, Germany

Competing Interests

KMW is an employee of Biocrates Life Sciences AG. This private company offers products and services in the field of targeted quantitative metabolomics research. The other authors have no competing interests to declare.

Author Contributions

Conceived and designed the experiments: CG JA TI KS. Performed the experiments: KMW. Analyzed the data: CG LG EA KS. Contributed reagents/materials/analysis tools: MHdA TM HWM HEW TI. Wrote the paper: CG FK KS.