About the Authors

Derrick E. Fouts

dfouts@jcvi.org

Affiliation J. Craig Venter Institute, Rockville, Maryland, United States of America

Heather L. Tyler

Affiliation Department of Microbiology and Cell Science, University of Florida, Gainesville, Florida, United States of America

Robert T. DeBoy

Affiliation J. Craig Venter Institute, Rockville, Maryland, United States of America

Sean Daugherty

Affiliation J. Craig Venter Institute, Rockville, Maryland, United States of America

Qinghu Ren

Affiliation J. Craig Venter Institute, Rockville, Maryland, United States of America

Jonathan H. Badger

Affiliation J. Craig Venter Institute, Rockville, Maryland, United States of America

Anthony S. Durkin

Affiliation J. Craig Venter Institute, Rockville, Maryland, United States of America

Heather Huot

Affiliation J. Craig Venter Institute, Rockville, Maryland, United States of America

Susmita Shrivastava

Affiliation J. Craig Venter Institute, Rockville, Maryland, United States of America

Sagar Kothari

Affiliation J. Craig Venter Institute, Rockville, Maryland, United States of America

Robert J. Dodson

Affiliation J. Craig Venter Institute, Rockville, Maryland, United States of America

Yasmin Mohamoud

Affiliation J. Craig Venter Institute, Rockville, Maryland, United States of America

Hoda Khouri

Affiliation J. Craig Venter Institute, Rockville, Maryland, United States of America

Luiz F. W. Roesch

Affiliation Department of Microbiology and Cell Science, University of Florida, Gainesville, Florida, United States of America

Karen A. Krogfelt

Affiliation Department of Bacteriology, Mycology and Parasitology, Statens Serum Institut, Copenhagen, Denmark

Carsten Struve

Affiliation Department of Bacteriology, Mycology and Parasitology, Statens Serum Institut, Copenhagen, Denmark

Eric W. Triplett

Affiliation Department of Microbiology and Cell Science, University of Florida, Gainesville, Florida, United States of America

Barbara A. Methé

Affiliation J. Craig Venter Institute, Rockville, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DEF YM HK KAK CS EWT. Performed the experiments: HLT YM HK KAK CS. Analyzed the data: DEF HLT RTD SD QR JHB ASD HH SS SK RJD YM HK LFWR KAK CS EWT BAM. Contributed reagents/materials/analysis tools: DEF HLT RTD SD QR JHB ASD HH SS SK RJD LFWR KAK CS EWT. Wrote the paper: DEF HLT RTD QR LFWR CS EWT BAM. Performed prophage analysis, comparative genomics, plant-induced and associated genes, animal-induced genes, protein secretion systems, antibiotic resistance mechanisms, and plasmids: DEF. Performed antibiotic resistance profiles and processing of mouse model data: HLT. Performed CRISPR and IS element analysis: RTD. Performed annotation: SD ASD HH SS SK RJD. Performed small molecule transporter analysis: QR. Performed phylogenetic tree building: JHB. Performed closure/finishing of the complete genome sequence: YM HK. Performed mouse model experiments: KAK CS. Carried out metabolism section: BAM.