About the Authors

Hualin Xi

Affiliation Bioinformatics Program, Boston University, Boston, Massachusetts, United States of America

Hennady P Shulha

Affiliation Biomedical Engineering Department, Boston University, Boston, Massachusetts, United States of America

Jane M Lin

Affiliation Biomedical Engineering Department, Boston University, Boston, Massachusetts, United States of America

Teresa R Vales

Affiliation Institute for Genome Sciences & Policy, Duke University, Durham, North Carolina, United States of America

Yutao Fu

Affiliation Bioinformatics Program, Boston University, Boston, Massachusetts, United States of America

David M Bodine

Affiliation Hematopoiesis Section, Genetics and Molecular Biology Branch, National Human Genome Research Institute, Bethesda, Maryland, United States of America

Ronald D. G McKay

Affiliation National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

Josh G Chenoweth

Affiliation National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

Paul J Tesar

Affiliation National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

Terrence S Furey

Affiliation Institute for Genome Sciences & Policy, Duke University, Durham, North Carolina, United States of America

Bing Ren

Affiliation Ludwig Institute for Cancer Research, University of California San Diego, La Jolla, California, United States of America

Zhiping Weng

To whom correspondence should be addressed. E-mail: greg.crawford@duke.edu (GEC); zhiping@bu.edu (ZW)

Affiliations Bioinformatics Program, Boston University, Boston, Massachusetts, United States of America , Biomedical Engineering Department, Boston University, Boston, Massachusetts, United States of America

Gregory E Crawford

To whom correspondence should be addressed. E-mail: greg.crawford@duke.edu (GEC); zhiping@bu.edu (ZW)

Affiliation Institute for Genome Sciences & Policy, Duke University, Durham, North Carolina, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

HX, ZW, and GEC conceived and designed the experiments. TV, JGC, PJT, and GEC performed the experiments. HX, HPS, JML, YF, TSF, ZW, and GEC analyzed the data. DMB, RDGM, and BR contributed reagents/materials/analysis tools. HX, JML, YF, ZW, and GEC wrote the paper.