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Signal transduction  
PLOS Computational Biology  
Mechanisms for dysregulation of excitatory-inhibitory balance underlying allodynia in dorsal horn neural subcircuits

Alexander G. Ginsberg, Scott F. Lempka, Bo Duan, Victoria Booth, Jennifer Crodelle

Research Article | published 14 Jan 2025 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012234

Views: 274Citations: 0Saves: 0 • Shares: 0

Learning predictive signatures of HLA type from T-cell repertoires

María Ruiz Ortega, Mikhail V. Pogorelyy, Anastasia A. Minervina, Paul G. Thomas, Thierry Mora, Aleksandra M. Walczak

Research Article | published 06 Jan 2025 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012724

Views: 366Citations: 0Saves: 0 • Shares: 0

Integration of partially observed multimodal and multiscale neural signals for estimating a neural circuit using dynamic causal modeling

Jiyoung Kang, Hae-Jeong Park

Research Article | published 23 Dec 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012655

Views: 326Citations: 0Saves: 0 • Shares: 0

Model supports asymmetric regulation across the intercellular junction for collective cell polarization

Katherine Levandosky, Calina Copos

Research Article | published 17 Dec 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012216

Views: 291Citations: 0Saves: 1 • Shares: 0

Dopamine facilitates the response to glutamatergic inputs in astrocyte cell models

Thiago Ohno Bezerra, Antonio C. Roque

Research Article | published 16 Dec 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012688

Views: 449Citations: 0Saves: 0 • Shares: 0

Mathematical basis and toolchain for hierarchical optimization of biochemical networks

Nisha Ann Viswan, Alexandre Tribut, Manvel Gasparyan, Ovidiu Radulescu, Upinder S. Bhalla

Methods | published 02 Dec 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012624

Views: 676Citations: 0Saves: 1 • Shares: 1

AI-powered simulation-based inference of a genuinely spatial-stochastic gene regulation model of early mouse embryogenesis

Michael Alexander Ramirez Sierra, Thomas R. Sokolowski

Research Article | published 14 Nov 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012473

Views: 695Citations: 0Saves: 0 • Shares: 0

Mechanical stress and anionic lipids synergistically stabilize an atypical structure of the angiotensin II type 1 receptor (AT1)

Rym Ben Boubaker, Daniel Henrion, Marie Chabbert

Research Article | published 13 Nov 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012559

Views: 438Citations: 0Saves: 1 • Shares: 1

Evolutionary history of calcium-sensing receptors unveils hyper/hypocalcemia-causing mutations

Aylin Bircan, Nurdan Kuru, Onur Dereli, Berkay Selçuk, Ogün Adebali

Research Article | published 12 Nov 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012591

Views: 996Citations: 0Saves: 0 • Shares: 0

Emergent order in epithelial sheets by interplay of cell divisions and cell fate regulation

Philip Greulich

Research Article | published 14 Oct 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012465

Views: 1114Citations: 0Saves: 0 • Shares: 1

Quantitative modeling of signaling in aggressive B cell lymphoma unveils conserved core network

Bertram Klinger, Isabel Rausch, Anja Sieber, Helmut Kutz, Vanessa Kruse, Marieluise Kirchner, Philipp Mertins, Arnd Kieser, Nils Blüthgen, Dieter Kube

Research Article | published 01 Oct 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012488

Views: 1007Citations: 0Saves: 1 • Shares: 1

Exploring the potential of structure-based deep learning approaches for T cell receptor design

Helder V. Ribeiro-Filho, Gabriel E. Jara, João V. S. Guerra, Melyssa Cheung, Nathaniel R. Felbinger, José G. C. Pereira, Brian G. Pierce, Paulo S. Lopes-de-Oliveira

Research Article | published 30 Sep 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012489

Views: 1798Citations: 1Saves: 0 • Shares: 0

Virus-host interactions predictor (VHIP): Machine learning approach to resolve microbial virus-host interaction networks

G. Eric Bastien, Rachel N. Cable, Cecelia Batterbee, A. J. Wing, Luis Zaman, Melissa B. Duhaime

Methods | published 18 Sep 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1011649

Views: 1891Citations: 2Saves: 0 • Shares: 2

The primacy model and the structure of olfactory space

Hamza Giaffar, Sergey Shuvaev, Dmitry Rinberg, Alexei A. Koulakov

Research Article | published 10 Sep 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012379

Views: 1141Citations: 2Saves: 9 • Shares: 16

Applying Super-Resolution and Tomography Concepts to Identify Receptive Field Subunits in the Retina

Steffen Krüppel, Mohammad H. Khani, Helene M. Schreyer, Shashwat Sridhar, Varsha Ramakrishna, Sören J. Zapp, Matthias Mietsch, Dimokratis Karamanlis, Tim Gollisch

Research Article | published 03 Sep 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012370

Views: 573Citations: 0Saves: 0 • Shares: 0

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