- A comprehensive exploration of the druggable conformational space of protein kinases using AI-predicted structures
-
Research Article | published 24 Jul 2024 PLOS Computational Biology
- Predicting the target landscape of kinase inhibitors using 3D convolutional neural networks
-
Research Article | published 05 Sep 2023 PLOS Computational Biology
- Elucidation of genome-wide understudied proteins targeted by PROTAC-induced degradation using interpretable machine learning
-
Research Article | published 17 Aug 2023 PLOS Computational Biology
- Systematic inference of indirect transcriptional regulation by protein kinases and phosphatases
-
Research Article | published 22 Jun 2022 PLOS Computational Biology
- Accurate, high-coverage assignment of in vivo protein kinases to phosphosites from in vitro phosphoproteomic specificity data
-
Research Article | published 13 May 2022 PLOS Computational Biology
- Characterization and clustering of kinase isoform expression in metastatic melanoma
-
Research Article | published 13 May 2022 PLOS Computational Biology
- KinPred: A unified and sustainable approach for harnessing proteome-level human kinase-substrate predictions
-
Research Article | published 08 Feb 2021 PLOS Computational Biology
- Predicting kinase inhibitors using bioactivity matrix derived informer sets
-
Research Article | published 05 Aug 2019 PLOS Computational Biology
- DeepConv-DTI: Prediction of drug-target interactions via deep learning with convolution on protein sequences
-
Research Article | published 14 Jun 2019 PLOS Computational Biology
- Integrated computational and Drosophila cancer model platform captures previously unappreciated chemicals perturbing a kinase network
-
Research Article | published 26 Apr 2019 PLOS Computational Biology
- On identifying collective displacements in apo-proteins that reveal eventual binding pathways
-
Research Article | published 15 Jan 2019 PLOS Computational Biology
- Computationally-guided drug repurposing enables the discovery of kinase targets and inhibitors as new schistosomicidal agents
-
Research Article | published 22 Oct 2018 PLOS Computational Biology
- Recognition of sites of functional specialisation in all known eukaryotic protein kinase families
-
Research Article | published 13 Feb 2018 PLOS Computational Biology
- Computational-experimental approach to drug-target interaction mapping: A case study on kinase inhibitors
-
Research Article | published 07 Aug 2017 PLOS Computational Biology
- Modelling of the cancer cell cycle as a tool for rational drug development: A systems pharmacology approach to cyclotherapy
-
Research Article | published 03 May 2017 PLOS Computational Biology
Results per page