Skip to main content
Advertisement
23 results for
Sort By:
Search Alert
Sign in to save this search alert

Filters:

Melanoma  
PLOS Computational Biology  
Using deep learning to decipher the impact of telomerase promoter mutations on the dynamic metastatic morpholome

Andres J. Nevarez, Anusorn Mudla, Sabrina A. Diaz, Nan Hao

Research Article | published 30 Jul 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1012271

Views: 712Citations: 0Saves: 5 • Shares: 1

A probabilistic knowledge graph for target identification

Chang Liu, Kaimin Xiao, Cuinan Yu, Yipin Lei, Kangbo Lyu, Tingzhong Tian, Dan Zhao, Fengfeng Zhou, Haidong Tang, Jianyang Zeng

Research Article | published 05 Apr 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1011945

Views: 1943Citations: 0Saves: 24 • Shares: 1

Unravelling cancer subtype-specific driver genes in single-cell transcriptomics data with CSDGI

Meng Huang, Jiangtao Ma, Guangqi An, Xiucai Ye

Research Article | published 14 Dec 2023 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1011450

Views: 1124Citations: 2Saves: 7 • Shares: 3

Explainable multi-task learning improves the parallel estimation of polygenic risk scores for many diseases through shared genetic basis

Adrien Badré, Chongle Pan

Research Article | published 07 Jul 2023 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1011211

Views: 1787Citations: 3Saves: 17 • Shares: 1

scAmpi—A versatile pipeline for single-cell RNA-seq analysis from basics to clinics

Anne Bertolini, Michael Prummer, Mustafa Anil Tuncel, Ulrike Menzel, María Lourdes Rosano-González, Jack Kuipers, Daniel Johannes Stekhoven, Tumor Profiler consortium , Niko Beerenwinkel, Franziska Singer

Research Article | published 03 Jun 2022 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1010097

Views: 8421Citations: 10Saves: 35 • Shares: 50

Characterization and clustering of kinase isoform expression in metastatic melanoma

David O. Holland, Valer Gotea, Kevin Fedkenheuer, Sushil K. Jaiswal, Catherine Baugher, Hua Tan, Michael Fedkenheuer, Laura Elnitski

Research Article | published 13 May 2022 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1010065

Views: 1885Citations: 5Saves: 10 • Shares: 3

A copula based topology preserving graph convolution network for clustering of single-cell RNA-seq data

Snehalika Lall, Sumanta Ray, Sanghamitra Bandyopadhyay

Research Article | published 10 Mar 2022 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1009600

Views: 2929Citations: 6Saves: 16 • Shares: 4

Combination treatment optimization using a pan-cancer pathway model

Robin Schmucker, Gabriele Farina, James Faeder, Fabian Fröhlich, Ali Sinan Saglam, Tuomas Sandholm

Research Article | published 28 Dec 2021 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1009689

Views: 2855Citations: 10Saves: 20 • Shares: 10

Transcriptomic profiling in canines and humans reveals cancer specific gene modules and biological mechanisms common to both species

Gregory J. Tawa, John Braisted, David Gerhold, Gurmit Grewal, Christina Mazcko, Matthew Breen, Gurusingham Sittampalam, Amy K. LeBlanc

Research Article | published 27 Sep 2021 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1009450

Views: 4328Citations: 15Saves: 38 • Shares: 14

ISOTOPE: ISOform-guided prediction of epiTOPEs in cancer

Juan L. Trincado, Marina Reixachs-Solé, Judith Pérez-Granado, Tim Fugmann, Ferran Sanz, Jun Yokota, Eduardo Eyras

Research Article | published 16 Sep 2021 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1009411

Views: 2487Citations: 8Saves: 34 • Shares: 20

Reproduction of patterns in melanocytic proliferations by agent-based simulation and geometric modeling

Günter Schneckenreither, Philipp Tschandl, Claire Rippinger, Christoph Sinz, Dominik Brunmeir, Nikolas Popper, Harald Kittler

Research Article | published 04 Feb 2021 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1008660

Views: 2440Citations: 2Saves: 25 • Shares: 5

Personalized logical models to investigate cancer response to BRAF treatments in melanomas and colorectal cancers

Jonas Béal, Lorenzo Pantolini, Vincent Noël, Emmanuel Barillot, Laurence Calzone

Research Article | published 28 Jan 2021 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1007900

Views: 3407Citations: 37Saves: 54 • Shares: 11

Multiobjective optimization identifies cancer-selective combination therapies

Otto I. Pulkkinen, Prson Gautam, Ville Mustonen, Tero Aittokallio

Research Article | published 28 Dec 2020 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1008538

Views: 2954Citations: 9Saves: 13 • Shares: 11

Determinants of combination GM-CSF immunotherapy and oncolytic virotherapy success identified through in silico treatment personalization

Tyler Cassidy, Morgan Craig

Research Article | published 27 Nov 2019 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1007495

Views: 4495Citations: 54Saves: 40 • Shares: 5

SCMarker: Ab initio marker selection for single cell transcriptome profiling

Fang Wang, Shaoheng Liang, Tapsi Kumar, Nicholas Navin, Ken Chen

Research Article | published 28 Oct 2019 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1007445

Views: 7248Citations: 35Saves: 63 • Shares: 27

Results per page

Save this search

Log in to save a search alert