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Histology  
PLOS Computational Biology  
STGIC: A graph and image convolution-based method for spatial transcriptomic clustering

Chen Zhang, Junhui Gao, Hong-Yu Chen, Lingxin Kong, Guangshuo Cao, Xiangyu Guo, Wei Liu, Bin Ren, Dong-Qing Wei

Research Article | published 28 Feb 2024 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1011935

Views: 1711Citations: 2Saves: 0 • Shares: 0

Mechanistic insight into the functional role of human sinoatrial node conduction pathways and pacemaker compartments heterogeneity: A computer model analysis

Jichao Zhao, Roshan Sharma, Anuradha Kalyanasundaram, James Kennelly, Jieyun Bai, Ning Li, Alexander Panfilov, Vadim V. Fedorov

Research Article | published 18 Dec 2023 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1011708

Views: 1160Citations: 1Saves: 1 • Shares: 4

Domestic cat nose functions as a highly efficient coiled parallel gas chromatograph

Zhenxing Wu, Jianbo Jiang, Fritz W. Lischka, Scott J. McGrane, Yael Porat-Mesenco, Kai Zhao

Research Article | published 29 Jun 2023 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1011119

Views: 4579Citations: 7Saves: 12 • Shares: 28

Deriving time-concordant event cascades from gene expression data: A case study for Drug-Induced Liver Injury (DILI)

Anika Liu, Namshik Han, Jordi Munoz-Muriedas, Andreas Bender

Research Article | published 10 Jun 2022 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1010148

Views: 2074Citations: 4Saves: 16 • Shares: 5

Reproduction of patterns in melanocytic proliferations by agent-based simulation and geometric modeling

Günter Schneckenreither, Philipp Tschandl, Claire Rippinger, Christoph Sinz, Dominik Brunmeir, Nikolas Popper, Harald Kittler

Research Article | published 04 Feb 2021 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1008660

Views: 2440Citations: 2Saves: 25 • Shares: 5

The interplay between cancer type, panel size and tumor mutational burden threshold in patient selection for cancer immunotherapy

Mahdi Golkaram, Chen Zhao, Kristina Kruglyak, Shile Zhang, Sven Bilke

Research Article | published 09 Nov 2020 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1008332

Views: 2340Citations: 4Saves: 11 • Shares: 2

CystAnalyser: A new software tool for the automatic detection and quantification of cysts in Polycystic Kidney and Liver Disease, and other cystic disorders

Adrián Cordido, Eva Cernadas, Manuel Fernández-Delgado, Miguel A. García-González

Research Article | published 22 Oct 2020 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1008337

Views: 4069Citations: 14Saves: 31 • Shares: 7

PyHIST: A Histological Image Segmentation Tool

Manuel Muñoz-Aguirre, Vasilis F. Ntasis, Santiago Rojas, Roderic Guigó

Research Article | published 19 Oct 2020 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1008349

Views: 6749Citations: 44Saves: 59 • Shares: 1

Machine Learning based histology phenotyping to investigate the epidemiologic and genetic basis of adipocyte morphology and cardiometabolic traits

Craig A. Glastonbury, Sara L. Pulit, Julius Honecker, Jenny C. Censin, Samantha Laber, Hanieh Yaghootkar, Nilufer Rahmioglu, Emilie Pastel, Katerina Kos, Andrew Pitt, Michelle Hudson, Christoffer Nellåker, Nicola L. Beer, Hans Hauner, Christian M. Becker, Krina T. Zondervan, Timothy M. Frayling, Melina Claussnitzer, Cecilia M. Lindgren

Research Article | published 14 Aug 2020 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1008044

Views: 5698Citations: 21Saves: 90 • Shares: 21

PenDA, a rank-based method for personalized differential analysis: Application to lung cancer

Magali Richard, Clémentine Decamps, Florent Chuffart, Elisabeth Brambilla, Sophie Rousseaux, Saadi Khochbin, Daniel Jost

Research Article | published 11 May 2020 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1007869

Views: 4116Citations: 12Saves: 32 • Shares: 7

Bioinformatics analysis of whole slide images reveals significant neighborhood preferences of tumor cells in Hodgkin lymphoma

Jennifer Hannig, Hendrik Schäfer, Jörg Ackermann, Marie Hebel, Tim Schäfer, Claudia Döring, Sylvia Hartmann, Martin-Leo Hansmann, Ina Koch

Research Article | published 21 Jan 2020 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1007516

Views: 4873Citations: 16Saves: 33 • Shares: 4

Evaluating reproducibility of AI algorithms in digital pathology with DAPPER

Andrea Bizzego, Nicole Bussola, Marco Chierici, Valerio Maggio, Margherita Francescatto, Luca Cima, Marco Cristoforetti, Giuseppe Jurman, Cesare Furlanello

Research Article | published 27 Mar 2019 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1006269

Views: 7881Citations: 54Saves: 138 • Shares: 21

On variational solutions for whole brain serial-section histology using a Sobolev prior in the computational anatomy random orbit model

Brian C. Lee, Daniel J. Tward, Partha P. Mitra, Michael I. Miller

Research Article | published 26 Dec 2018 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1006610

Views: 3814Citations: 21Saves: 22 • Shares: 1

Simulation enabled search for explanatory mechanisms of the fracture healing process

Ryan C. Kennedy, Meir Marmor, Ralph Marcucio, C. Anthony Hunt

Research Article | published 02 Feb 2018 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1005980

Views: 2237Citations: 4Saves: 22 • Shares: 4

Histologic and biochemical alterations predict pulmonary mechanical dysfunction in aging mice with chronic lung inflammation

Christopher B. Massa, Angela M. Groves, Smita U. Jaggernauth, Debra L. Laskin, Andrew J. Gow

Research Article | published 24 Aug 2017 PLOS Computational Biology

https://doi.org/10.1371/journal.pcbi.1005570

Views: 4550Citations: 12Saves: 24 • Shares: 4

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