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Open Access
Peer-reviewed
Research Article
Population-specific design of de-immunized protein biotherapeutics
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Benjamin Schubert ,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: benjamin_schubert@hms.harvard.edu
Affiliations Center for Bioinformatics, University of Tübingen, Tübingen, Germany, Applied Bioinformatics, Dept. of Computer Science, Tübingen, Germany, Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America
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Charlotta Schärfe,
Roles Investigation, Writing – original draft, Writing – review & editing
Affiliations Center for Bioinformatics, University of Tübingen, Tübingen, Germany, Applied Bioinformatics, Dept. of Computer Science, Tübingen, Germany, Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America
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Pierre Dönnes,
Roles Data curation, Writing – original draft, Writing – review & editing
Affiliations Center for Bioinformatics, University of Tübingen, Tübingen, Germany, SciCross AB, Skövde, Sweden
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Thomas Hopf,
Roles Software, Writing – original draft, Writing – review & editing
Affiliations Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America
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Debora Marks ,
Contributed equally to this work with: Debora Marks, Oliver Kohlbacher
Roles Formal analysis, Resources, Writing – original draft, Writing – review & editing
Affiliation Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America
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Oliver Kohlbacher
Contributed equally to this work with: Debora Marks, Oliver Kohlbacher
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing
Affiliations Center for Bioinformatics, University of Tübingen, Tübingen, Germany, Applied Bioinformatics, Dept. of Computer Science, Tübingen, Germany, Quantitative Biology Center, Tübingen, Germany, Faculty of Medicine, University of Tübingen, Tübingen, Germany, Biomolecular Interactions, Max Planck Institute for Developmental Biology, Tübingen, Germany
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Population-specific design of de-immunized protein biotherapeutics
- Benjamin Schubert,
- Charlotta Schärfe,
- Pierre Dönnes,
- Thomas Hopf,
- Debora Marks,
- Oliver Kohlbacher
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- Published: March 2, 2018
- https://doi.org/10.1371/journal.pcbi.1005983