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Open Access
Peer-reviewed
Research Article
Comprehensive Sieve Analysis of Breakthrough HIV-1 Sequences in the RV144 Vaccine Efficacy Trial
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Paul T. Edlefsen ,
* E-mail: pedlefse@fredhutch.org
¶‡ These authors contributed equally to this work.
Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯ -
Morgane Rolland ,
¶‡ These authors contributed equally to this work.
Affiliation US Military HIV Research Program, Silver Spring, Maryland, United States of America
⨯ -
Tomer Hertz ,
¶‡ These authors contributed equally to this work.
Affiliations Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, The Shraga Segal Dept. of Microbiology, Immunology and Genetics, Faculty of Health Sciences, and The National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva, Israel
⨯ -
Sodsai Tovanabutra ,
¶‡ These authors contributed equally to this work.
Affiliation US Military HIV Research Program, Silver Spring, Maryland, United States of America
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Andrew J. Gartland,
Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
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Allan C. deCamp,
Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯ -
Craig A. Magaret,
Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯ -
Hasan Ahmed,
Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
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Raphael Gottardo,
Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯ -
Michal Juraska,
Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯ -
Connor McCoy,
Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯ -
Brendan B. Larsen,
Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America
⨯ -
Eric Sanders-Buell,
Affiliation US Military HIV Research Program, Silver Spring, Maryland, United States of America
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Chris Carrico,
Affiliations Department of Biochemistry, University of Washington, Seattle, Washington, United States of America, IAVI Neutralizing Antibody Center and Department of Immunology and Microbial Sciences, The Scripps Research Institute, La Jolla, California, United States of America
⨯ -
Sergey Menis,
Affiliations Department of Biochemistry, University of Washington, Seattle, Washington, United States of America, IAVI Neutralizing Antibody Center and Department of Immunology and Microbial Sciences, The Scripps Research Institute, La Jolla, California, United States of America
⨯ -
Meera Bose,
Affiliation US Military HIV Research Program, Silver Spring, Maryland, United States of America
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RV144 Sequencing Team ,
¶Membership of the RV144 Sequencing Team is provided in the Acknowledgments.
⨯ -
Miguel A. Arroyo,
Affiliation Royal Thai Army Component, AFRIMS, Bangkok, Thailand
⨯ -
Robert J. O’Connell,
Affiliation US Army Component, AFRIMS, Bangkok, Thailand
⨯ -
Sorachai Nitayaphan,
Affiliation Royal Thai Army Component, AFRIMS, Bangkok, Thailand
⨯ -
Punnee Pitisuttithum,
Affiliation Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
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Jaranit Kaewkungwal,
Affiliation Royal Thai Army Component, AFRIMS, Bangkok, Thailand
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Supachai Rerks-Ngarm,
Affiliation CDC Department, Thai Ministry of Public Health, Nonthaburi, Thailand
⨯ -
Merlin L. Robb,
Affiliation US Military HIV Research Program, Silver Spring, Maryland, United States of America
⨯ -
Tatsiana Kirys,
Affiliation Vaccine Research Center, NIAID, NIH, Bethesda, Maryland, United States of America
⨯ -
Ivelin S. Georgiev,
Affiliation Vaccine Research Center, NIAID, NIH, Bethesda, Maryland, United States of America
⨯ -
Peter D. Kwong,
Affiliation Vaccine Research Center, NIAID, NIH, Bethesda, Maryland, United States of America
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Konrad Scheffler,
Affiliation Department of Medicine, University of California, San Diego, La Jolla, California, United States of America
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Sergei L. Kosakovsky Pond,
Affiliation Department of Medicine, University of California, San Diego, La Jolla, California, United States of America
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Jonathan M. Carlson,
Affiliation eSience Research Group, Microsoft Research, Redmond, Washington, United States of America
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Nelson L. Michael,
Affiliation US Military HIV Research Program, Silver Spring, Maryland, United States of America
⨯ -
William R. Schief,
Affiliations Department of Biochemistry, University of Washington, Seattle, Washington, United States of America, IAVI Neutralizing Antibody Center and Department of Immunology and Microbial Sciences, The Scripps Research Institute, La Jolla, California, United States of America, Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America
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James I. Mullins,
Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America
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Jerome H. Kim,
Affiliation US Military HIV Research Program, Silver Spring, Maryland, United States of America
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Peter B. Gilbert
Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
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Comprehensive Sieve Analysis of Breakthrough HIV-1 Sequences in the RV144 Vaccine Efficacy Trial
- Paul T. Edlefsen,
- Morgane Rolland,
- Tomer Hertz,
- Sodsai Tovanabutra,
- Andrew J. Gartland,
- Allan C. deCamp,
- Craig A. Magaret,
- Hasan Ahmed,
- Raphael Gottardo,
- Michal Juraska
- Published: February 3, 2015
- https://doi.org/10.1371/journal.pcbi.1003973