Skip to main content
Advertisement

Assessment of mutation probabilities of KRAS G12 missense mutants and their long-timescale dynamics by atomistic molecular simulations and Markov state modeling

  • Tatu Pantsar ,

    Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

    tatu.pantsar@uef.fi (TP); antti.poso@uef.fi (AP)

    Affiliation School of Pharmacy, University of Eastern Finland, Kuopio, Finland

  • Sami Rissanen,

    Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

    Affiliation Laboratory of Physics, Tampere University of Technology, Tampere, Finland

  • Daniel Dauch,

    Roles Validation, Writing – review & editing

    Affiliations Department of Internal Medicine VIII, University Hospital Tuebingen, Tuebingen, Germany, Department of Physiology I, Institute of Physiology, Eberhard Karls University Tuebingen, Tuebingen, Germany

  • Tuomo Laitinen,

    Roles Conceptualization, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

    Affiliation School of Pharmacy, University of Eastern Finland, Kuopio, Finland

  • Ilpo Vattulainen,

    Roles Conceptualization, Funding acquisition, Resources, Supervision, Validation, Writing – review & editing

    Affiliations Laboratory of Physics, Tampere University of Technology, Tampere, Finland, Department of Physics, University of Helsinki, Helsinki, Finland, MEMPHYS-Center for Biomembrane Physics, Helsinki, Finland

  • Antti Poso

    Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

    tatu.pantsar@uef.fi (TP); antti.poso@uef.fi (AP)

    Affiliations School of Pharmacy, University of Eastern Finland, Kuopio, Finland, Department of Internal Medicine VIII, University Hospital Tuebingen, Tuebingen, Germany

Viewed

Total Article Views
11,667
Sep 10, 2018 (publication date)
through Jan 28, 2025 *
MonthsCumulative Views12345678910111213141516171819202122232425262728293031323334353637383940414243444546474849505152535455565758596061626364656667686970717273747576770k5k10k15k

*Although we update our data on a daily basis, there may be a 48-hour delay before the most recent numbers are available.

Cited

Saved

Discussed

0 Wikipedia
4 twitter
1 Facebook
0 reddit
Powered by Altmetric
Questions or concerns about usage data? Please let us know.