The benchmark simulations were conducted in a Docker container on Intel Xeon(R) Gold 6136 CPU @ 3.00 GHz x 48 machine with 376.6 GB of memory, with disabled MPI, i.e. only on one core, and up to 128 GB used by OSS-DBS. The adaptive mesh refinement for the human and the rat brain tissue took 1 hour 46 minutes and 3 hours 54 minutes, respectively.