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Fig 1.

The model architecture of Image2Flow.

The hybrid image and graph convolutional neural network architecture of Image2Flow. It takes as input a 3D cardiac MRI and a template volume mesh of a pulmonary artery. It outputs the patient-specific pulmonary artery mesh with associated pressure and flow at each node.

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Fig 2.

A schematic of the steps involved in point-point correspondent volume mesh generation.

(A) raw patient-specific volume mesh created from manual segmentation, (B) initial template volume mesh creation, (C) point-point correspondent volume mesh generation by transforming the initial template, (D) final template volume mesh creation by averaging the point-point correspondent meshes of the training data. Red indicates non-corresponding meshes and blue represents corresponding meshes. The wireframe rendering denotes surface meshes, while the solid rendering denotes volume meshes.

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Fig 3.

Segmentation accuracy.

The best, median and worst Image2Flow segmentations compared to ‘MeshDeformNet’ and a 3D UNet.

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Table 1.

Segmentation metrics evaluating Image2Flow, ‘MeshDeformNet’ and the 3D UNet compared to the ground truth.

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Table 1 Expand

Fig 4.

(A) MNAES values of the Image2Flow predictions compared to the ground truth on the test set (n = 15) for pressure and velocity. (B) Difference in MNAES values between CFDI2F and CFDDL-seg.

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Fig 5.

The best, median and worst blood pressure, and velocity predictions of Image2Flow by MNAEs.

The size and positioning between the true and predicted meshes are to scale.

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Fig 6.

The distribution of node-wise error (MNAEN) of the test set (n = 15) projected onto the template pulmonary artery volume-mesh.

(A) Distribution of error across the cross-section of the pulmonary artery, (B) Bland-Altman analysis of the pressure and velocity magnitude errors.

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Fig 7.

MNAES values of the Image2Flow pressure and velocity magnitude predictions for different inlet velocities (0.1, 0.2, and 0.3m/s).

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Fig 8.

The best, median and worst blood pressure predictions of Image2Flow with varying input inlet velocity (0.1–0.3m/s).

The size and positioning between the true and predicted meshes are to scale.

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Fig 9.

The best, median and worst blood velocity predictions of Image2Flow with varying input inlet velocity (0.1–0.3m/s).

The size and positioning between the true and predicted meshes are to scale.

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Fig 10.

Comparison between Image2Flow CFD prediction and conventional CFD on the same geometry.

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