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Table 1.

A summary of AWS pricing for basic computation, storage, and data transfer.

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Figure 1.

Step-wise framework for creating a scalable NGS computing application.

Using your local computer, ssh into an instance running in AWS. The costs are representative of actual development time, data transfer into and out of the cloud, and the compute time using AWS (Table 1). The costs presented may vary, as AWS frequently updates their pricing structure. (A) An additional 3 hours were included for installing programs and testing the instance for the prototyping phase. (B) An additional 2 hours were included in developing the scalable application to learn how to use the cluster management software. (C) For the final scaled application, we used a 38-instance cluster.

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