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VAMPr: VAriant Mapping and Prediction of antibiotic resistance via explainable features and machine learning

Fig 4

Validation performance metrics using an external dataset.

AUROC (Area under the Receiver Operating Characteristic) for the prediction of the external dataset and top three predictors (KEGG orthlog variants based on importance) from the prediction models are reported. A) The AUROC curve for the E. coli and meropenem; B) The AUROC curve for the K. pneumoniae and ceftazidime; C) The AUROC curve for the P. aeruginosa and meropenem; D) The top three predictors for the E. coli and meropenem; E) The top three predictors for the K. pneumoniae and ceftazidime; F) The top three predictors for the P. aeruginosa and meropenem.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1007511.g004