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EAGLE: An algorithm that utilizes a small number of genomic features to predict tissue/cell type-specific enhancer-gene interactions

Fig 6

Predicted EG interactions are enriched for eQTLs.

(A) Percentages of tissue-specific eQTLs overlapping with interacting and non-interacting pairs, respectively. The eQTL datasets were from the corresponding tissue types that we used to predict enhancer-target gene pairs. (B) Significance (p-values) of eQTLs overlapping with interacting and non-interacting enhancer-target pairs. *P < 0.01; **P < 1e-16; n.s. not significant. (C) Percentages of interacting and non-interacting pairs overlapping with eQTLs combined from 48 tissues.

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1007436.g006