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Predicting synthetic lethal interactions using conserved patterns in protein interaction networks

Fig 1

A schematic visualising how SLant’s source data is collated from STRING and the Gene Ontology Consortium, preprocessed so that this source data can be directed joined with BioGRID data for labeling and processed to create the final training set.

Feature generation was completed using R, the R igraph library and GoSemSim, a Bioconductor package.

Fig 1